by Marion Nestle

Search results: antibiotics

Jan 25 2022

Maybe a hint of good news about animal antibiotics?

The FDA says use of medically important antimicrobial drugs in food animals decreased by 3% between 2019 and 2020  (For details, see the full report).

Is this good news or not.  Use is down from 2015-2016, but up from 2017.  As Wired puts it, “Antibiotic Use in US Farm Animals Was Falling. Now It’s Not.”

According to the Natural Resource Defense Council, use of antibiotics as growth promoters in food animals is still a big problem, with lots more going for use in animals than in humans.

Or, to be a bit more precise:

The Pew Foundation thinks much more needs to be done to limit use of antibiotics in food animals.

FDA: get on this please.

Feb 13 2018

Overuse of antibiotics in animal agriculture: more data (still no action)

An article in The Guardian alerted me to a new report comparing antibiotic use in the UK to that in the US.  The Guardian explains the problem:

The contribution of farm antibiotic use to human resistance is widely recognised, including by the 2016 O’Neill AMR report, the World Health Organisation and the European Food Safety Authority.

The routine overuse of antibiotics in farm animals creates perfect conditions for the emergence of resistant bacteria, killing off susceptible bacteria while allowing stronger resistant bacteria to survive.

The report comes from the UK advocacy group, Alliance to Save Our Antibiotics.

The report finds that per ton of livestock, antibiotic:

  • Use in US pigs is about twice as high as use in UK pigs.
  • Use in US chickens is about 3 times as high as use in UK chickens.
  • Use in US turkeys is about 5 times as high as use in UK turkeys.
  • Use in US cattle is about 9-16 times as high as use in UK cattle.
  • Use in all food animals in the US is about 5 times as high as use in the UK.

The report includes a table of US sales of medically important antibiotics (kilograms active ingredient):This group has lots of other reports on specific aspects of antibiotic use, including one from October 2017 on farm antibiotic use in the U.S.

The FDA, which has an entire web page on animal antibiotics, has made valiant efforts over the years to control antibiotic use in farm animals, but these have not gotten very far.

The threat to the effectiveness of antibiotics in humans is real and affects all of us.  At least 20 organizations in the US are advocating for more responsible use of antibiotics in farm animals.

Their efforts deserve support.

Nov 14 2017

WHO: Restrict medically important antibiotics in farm animals

The World Health Organization has issued guidelines on use of medically important antibiotics in food-producing animalsIts latest report recommends:

  • An overall reduction in use
  • Complete restriction in use for growth promotion
  • Complete restriction of use for infectious disease prevention
  • Not using them for disease treatment

For comparison, the FDA bans these antibiotics for growth promotion, but permits when recommended by a veterinarian when necessary for an animal’s health.

Antibiotics used in food animal production amount to 80 percent of antibiotic consumption worldwide.

Studies show that restricting antibiotic use in animals will reduce their prevalence of bacteria resistant to antibiotics.

As you might expect, opinions about this report are divided.  Consumer groups, who have been advocating for these practices for years, are eager for the guidelines to be implemented immediately.  So are companies like Perdue, which are already doing this.

Opposition comes from the meat industry, of course, but also the chief scientist of USDA who must not have read the guidelines carefully, if at all.

The WHO guidelines are not in alignment with U.S. policy and are not supported by sound science. The recommendations erroneously conflate disease prevention with growth promotion in animals.

The WHO report may help advocates get some long-awaited action on antibiotics, but it’s hard to be optimistic.

I just came across this report from the CDC: 2017 Antibiotic use in the U.S.: Progress and Opportunities It is This report is notable for focusing exclusively on antibiotics in human health.  It excludes any discussion of antibiotic use in animals—as if there were no relationship.

It’s time to bring agricultural policies in line with health policies!

Oct 26 2017

Meat on the agenda: Bacon and Fast Food antibiotics

I’m collecting reports about meat.

The first is The Bacon Report from MeatPoultry.com.

 

And here’s Restaurant Report Card: What’s in your fast food meat?

May 10 2017

Will we ever stop misusing animal antibiotics?

Politico ProAg reports that the International Poultry Council will soon issue a statement advising the poultry industry to:

  • Stop using antibiotics critical to human medicine to promote livestock growth and prevent disease,
  • Only use these drugs when prescribed by a veterinarian for treatment of disease,
  • Be transparent about the amount of antibiotics it uses and why.

The poultry industry routinely uses antibiotics in feed and water despite major efforts to stop this practice.

Government agencies concerned about increasing resistance to animal antibiotics have long wanted their use stopped or managed appropriately.

Trying to stop misuse of animal antibiotics has a long history.

The animal agriculture industry has fought all attempts to curtain antibiotic use.

The word has gotten through to the poultry industry.  Let’s hope this works.

Dec 27 2013

More on “profligate” use of antibiotics to promote growth in farm animals

The New England Journal of Medicine has an editorial on why we need to stop using antibiotics to promote the growth of farm animals and make sure they are only used for therapeutic purposes.

Otherwise, bacteria will become resistant to them and the antibiotics won’t work in us.

This figure from the article illustrates the problem:

As writers in the Journal wrote a year ago, we know what to do about the problem: Ban antibiotic use for everything other than disease treatment.

The FDA is taking baby steps in this direction.  How about a new year’s resolution to speed up the process?

Dec 17 2013

The FDA issues guidance on animal antibiotics–voluntary, alas, but still a major big deal

I was in Washington DC last week when the FDA announced  that it was taking significant steps to address antibiotic resistance, a problem caused by overuse in raising animals for food.

The FDA called on makers of animal antibiotics to:

  • Voluntarily stop labeling medical important antibiotics as usable for promoting animal growth or feed efficiency (in essence, banning antibiotics from these uses).
  • Voluntarily notify the FDA of their intent to sign on to these strategies within the next three months.
  • Voluntarily put the new guidance into effect within 3 years.
  • Agree to a proposed rule to require a veterinarian’s prescription to use antibiotics that are presently sold over the counter (the proposal is open for public comment for 90 days at www.regulations.gov.   Docket FDA-2010-N-0155).

Voluntary is, of course, a red flag and the Washington Post quoted critics saying that the new guidance falls far short of what really is needed—a flat-out ban on use of antibiotics as growth promoters.

  • Consumers Union is concerned about the long delay caused by the 3-year window.
  • CSPI is worried about all the loopholes.
  • NRDC thinks the FDA is pretending to do more than it’s really doing and “kicks the can significantly down the road.”
  • Mother Jones points out that the meat industry can still “claim it’s using antibiotics ‘preventively,’ continuing to reap the benefits of growth promotion and continue to generate resistant bacteria.”
  • Civil Eats reminds us that the Pew Commission on Industrial Farm Animal Production (on which I served) recommended a ban on nontherapeutic use of all antibiotics.

Yes, the loopholes are real, but I view the FDA’s guidance as a major big deal.  The agency is explicitly taking on the antibiotic problem.  It is sending a clear signal to industrial farm animal  producers that sooner or later they will have to:

  • Stop using antibiotics as growth promoters.
  • Stop using antibiotics indiscriminately, even for disease treatment.

I think the FDA is dead serious about the antibiotic problem.  If the FDA seems to be doing this in some convoluted fashion, I’m guessing it’s because it has to.  The FDA must not have been able to find any other politically viable way to get at the antibiotics problem.

I see this as a first step on the road to banning antibiotics for any use in animals other than the occasional treatment of specific illnesses.

As the New York Times puts it,

This is the agency’s first serious attempt in decades to curb what experts have long regarded as the systematic overuse of antibiotics in healthy farm animals, with the drugs typically added directly into their feed and water. The waning effectiveness of antibiotics — wonder drugs of the 20th century — has become a looming threat to public health. At least two million Americans fall sick every year and about 23,000 die from antibiotic-resistant infections.

Still not convinced antibiotics are worth banning for promoting growth?

The best explanation is the Washington Post’s handy guide to the antibiotic-perplexed.  Here, for example, is its timeline of development of microbial resistance to antibiotics.  The bottom line: the more widespread the use of antibiotics, the greater the onset and prevalence of resistance.  And it takes practically no time for bacteria to develop resistance to antibiotic drugs.

nchembio.2007.24-F1

Resources from FDA

Apr 12 2012

The FDA takes action on animal antibiotics, at long last

Yesterday, the FDA proposed long-awaited action against use of antibiotics for non-therapeutic purposes in animal agriculture.

From the outside, this might look more like inaction.  The agency is asking drug companies to voluntarily cut back on producing antibiotics for non-therapeutic purposes and to require veterinary oversight of use of these drugs.

The announcement comes in the form of three documents in the Federal Register.

  • Final Guidance for Industry: The Judicious Use of Medically Important Antimicrobial Drugs in Food-Producing Animals.
  • Draft Guidance for Industry aimed at assisting drug companies in voluntarily removing from FDA-approved product labels uses of antibiotics for production rather than therapy, and voluntarily changing the marketing status to include veterinary oversight.  This is open for public comment.
  • A draft of a proposed Veterinary Feed Directive regulation,  also open for public comment, outlining how veterinarians can authorize the use of antibiotics in animal feed.

In an FAQ on the announcement, the FDA answers some obvious questions:

4. What is “judicious use” and what are FDA’s recommendations?

“Judicious use” is using an antimicrobial drug appropriately and only when necessary;

Based on a thorough review of the available scientific information, FDA recommends that use of medically important antimicrobial drugs in food-producing animals be limited to situations where the use of these drugs is necessary for ensuring animal health, and their use includes veterinary oversight or consultation.

FDA believes that using medically important antimicrobial drugs to increase production in food-producing animals is not a judicious use (my emphasis).

5. Why did FDA decide to do this now?

FDA has worked with many stakeholder groups and the U.S. Department of Agriculture (USDA) to develop a strategy that will be successful in reducing antimicrobial resistance while minimizing adverse impacts on animal health and disruption to the animal agricultural industry.

In June 2010, FDA released a draft guidance document explaining its recommendations for change and in the interim period sought and received input from various stakeholders, including the animal pharmaceutical industry, animal feed industry, veterinary and animal producer communities, consumer advocacy groups and USDA.

Translation: this has been in the works for a long time and is the result of extensive discussions with the relevant industries.

As Food Safety News explains, the reaction of just about everyone to this announcement has been tepid.

  • Food safety advocates object to voluntary, because it never works.
  •  The meat industry insists that non-therapeutic antibiotics are essential for producing cheap meat under crowded conditions.

For example, the National Pork Producers make the usual industry arguments:

Harm to small farmers: The guidance could eliminate antibiotics uses that are extremely important to the health of animals…And the requirement for VFDs [veterinary oversight] could be problematic, particularly for smaller producers or producers in remote areas who may not have regular access to veterinary services.

Voluntary equals regulation: The guidance, which does not have the force of law but may be treated as such by FDA, is a move to address an increase in antibiotic-resistant illnesses in humans, which opponents of modern animal agriculture blame on the use of antibiotics in livestock and poultry production.

The science is “junk”: But numerous peer-reviewed risk assessments, including at least one by FDA, show a “negligible” risk to human health of antibiotics use in food-animal production.

My interpretation:

The FDA’s position on non-therapeutic use of antibiotics in animal agriculture is quite clear.  The agency recognizes that based on the science, the use of antibiotics as growth promoters in animals poses a serious risk to human health.

I’m guessing this is the best the FDA can do in an election year.

This move looks to me like a direct challenge to drug companies and meat producers to clean up their acts and take some responsibility for the effects of their misuse of animal antibiotics on public health.

It’s also a challenge to food safety advocates to make sure that the FDA monitors the effects of its voluntary guidance and, if the industries don’t cooperate, that the FDA gets busy on real regulations.

Addition: The account in today’s New York Times explains why the FDA is starting with voluntary efforts:

The reason for the reliance on voluntary efforts is that the F.D.A.’s process for revoking approved drug uses is lengthy and cumbersome, officials said. The last time the F.D.A. banned an agricultural use of a medically important antibiotic against the wishes of its maker, legal appeals took five years. In this case, hundreds of drugs are involved, each with myriad approved uses in various animals.

“You and I and our children would be long dead before F.D.A. could restrict all of these uses on its own,” Ms. Rogers [of the Pew Foundation]said.