I’ve just gotten a notice that a big study in Critical Reviews in Toxicology gives aspartame a clean bill of health; the reviewers judge it safe at current levels of intake and find “no credible scientific basis” to think otherwise. This comment refers to contrary studies first published a year or so ago and confirmed again this summer by an Italian group (see their paper in Environmental Health Perspectives). This group claims that aspartame causes cancer in rats when consumed at levels typical of those in soft drinks. The Critical Reviews analysis is the most recent of many other such studies discounting the methods and opinions of aspartame critics. Will this latest study–at long last–put the matter to rest? I doubt it. The Critical Reviews analysis was funded by the maker of aspartame, Ajinomoto. Even though its authors were not told this, and the sponsor was not involved in the review, the study gives the appearance of conflict of interest. This kind of sponsorship is not helpful. My own view (which I discuss in detail in What to Eat) is that aspartame probably is safe at current levels of intake. But so what? It is an artificial sweetener. I don’t like anything artificial when it comes to food and I much prefer sugar (in moderation, of course).