by Marion Nestle

Currently browsing posts about: Conflicts-of-interest

Sep 10 2015

Industry-funded studies with results that do NOT favor the sponsor! The score since March: 50:3

Since mid-March, I’ve been collecting research studies funded by food companies or trade associations, and dividing them into those that come out with results favorable to the sponsor (50 so far–this is a corrected number) and those that do not (as of today, 3).

As always, if you run across others, please send.

A reader, Cole Adam, sent me this study on dark chocolate funded by a Finnish company that makes chocolate products.

Dark chocolate and reduced snack consumption in mildly hypertensive adults: an intervention study.  Raika Koli, Klaus Köhler, Elina Tonteri, Juha Peltonen, Heikki Tikkanen and Mikael Fogelholm.  Nutrition Journal 2015, 14:84  doi:10.1186/s12937-015-0075-3

  • Results: Daily consumption of dark chocolate had no effects on 24 h blood pressure, resting blood pressure…or arterial stiffness.  Weight was reduced by 1.0 ± 2.2 kg during the control (reduced snack only) period, but was unchanged while eating chocolate (p < 0.027 between the treatments).
  • Conclusion:  …inclusion of 49 g dark chocolate daily as part of a diet of mildly hypertensive participants had no significant effects on cardiovascular risk factors during 8 wks.  Apart from a small effect on body weight (dark chocolate seemingly prevented a slight decrease in body weight during the control period), no other negative effects were observed.
  • Funding:  This work was funded by Oy Karl Fazer Ab. Authors declare no competing interests regarding this study.  [Oy Karl Fazer Ab sells bakery, biscuit, and confectionery products in Finland, Sweden, Estonia, Latvia, Lithuania, Norway, Denmark, Russia, and internationally]

Several points to note about this study:

  • Eating 49 grams (just under 2 ounces) of dark chocolate a day may be fun, but it is not going to reduce your blood pressure.
  • Eating 49 grams of dark chocolate a day makes weight loss more difficult.
  • The authors do not view corporate funding as introducing competing interests.  OK.  Maybe not in this case, but this is a rare exception.

Another reader, who prefers to remain anonymous, sent this one:

Milk intake is not associated with low risk of diabetes or overweight-obesity: a Mendelian randomization study in 97,811 Danish individualsHelle KM Bergholdt, Børge G Nordestgaard, and Christina Ellervik.  Am J Clin Nutr 2015;102:487–96. 

  • Conclusions: High milk intake is not associated with a low risk of type 2 diabetes or overweight-obesity, observationally or genetically via lactase persistence.  The higher risk of type 2 diabetes in   individuals without milk intake likely is explained by collider stratification bias.
  • Conflict: HKMB’s PhD project was partly funded by the Research Unit at Naestved Hospital, the Danish Dairy Research Foundation, and the Regional Research Unit in Region Zealand. [The population studies were funded by a long list of government agencies, health organizations, and foundations].
  • Comment: This study says that high milk intake is associated with a higher risk of type 2 diabetes, although it explains it away.  The Danish dairy industry paid for part of the first author’s dissertation research.  It looks like most of the funding came from independent sources, so this one is a bit of a stretch, but to be super scrupulous let’s count it as industry-funded.

NOTE: All three “negative” studies I’ve posted since March were funded by international food companies (the previous one was funded by the Danish Dairy Research Foundation).

Sep 8 2015

Should scientists with financial ties to Monsanto be subject to FOIA requests?

Sunday’s New York Times story on academic conflicts of interest focused on scientists with financial ties to Monsanto.  The ties were revealed by open-records requests for e-mails and other information.

The Times was not the only one to make these requests.  U.S. Right to Know, a group devoted to investigating Big Food and its front groups had already done so.  U.S. Right to Know is funded primarily by the Organic Consumers Association, a national grassroots network advocating for organics, sustainability, and food safety—but against GMOs.

U.S. Right to Know rightfully takes credit for establishing the basis of the Times’ story.  It sent open-records requests to scientists working for public institutions who seemed likely to have financial ties to Monsanto.  Bingo.  Some of the e-mails revealed such ties.*

But should government-funded scientists be subjected to open records requests?  Couldn’t these requests amount to open season on academics—a modern-day version of witchhunts?  This question is now under active debate (and see comments on my previous post).

While these debates are raging, here is one aspect of this story that the New York Times did not tell.

Earlier this month, Paul Thacker and my NYU colleague Charles Seife, wrote a piece for PLoS [Public Library of Science] Blogs arguing that Freedom of Information Act (FOIA) requests “for personal correspondence are not just appropriate, but crucial to ensuring transparency.”   They argue that the benefits of transparency outweigh the costs.

But transparency laws remain a fundamental tool for monitoring possible scientific misbehavior. And it would be a mistake to believe that scientists should not be subject to a high level of outside scrutiny. So long as scientists receive government money, they are subject to government oversight; so long as their work affects the public, journalists and other watchdogs are simply doing their jobs when they seek out possible misconduct and questionable practices that could threaten the public interest.

Thacker and Seife explain:

Last week, Nature reported that the University of Florida had provided them with emails that U.S. Right to Know had FOIA’d on one of their researchers…the [Nature] story noted that the researcher has received money from Monsanto to fund expenses incurred while giving educational talks on GMOs.  The article also noted that the PR Firm Ketchum had provided the scientist with canned answers to respond to GMO critics, although it is unclear if he used them [the Times story says he did but now regrets it].

The article does not report that the scientist has repeatedly denied having a financial relationship with Monsanto. The article also does not report on an email titled “CONFIDENTIAL: Coalition Update” from the researcher to Monsanto in which the scientist advised Monsanto on ways to defeat a political campaign in California to require labeling of GMO products.

Some readers of PLoS were outraged that this online journal would publish an article supporting open-records requests of scientists (see, for example, this from the American Council on Science and Health).

Here’s where things get interesting.

PLoS responded to the criticism by, of all things, retracting the article.

Seife and Thacker explained their views in an op-ed in the Los Angeles Times.

If the public pays your salary, citizens have the right — within limits — to see what you’re doing. That’s the principle at the core of the federal Freedom of Information Act and of the many similar state freedom of information laws… “snooping” on scientists’ inboxes by journalists, watchdogs and government officials has revealed significant problems that would never have come to light via other means.

That, of course, is the basis of the New York Times’ exposé of Monsanto’s funding of scientists to testify on the company’s behalf to reporters, Congress, and the public.

Bottom line: Because industry-funded science and scientists almost invariably provide data and testimony that favors the sponsors interests, the press and public need to know about sponsorship.

One more comment:  A substantial body of literature exists on industry sponsorship of science, particularly on the effects of pharmaceutical industry funding of medical professionals.  Conflicts-of-interest researchers conclude that such conflicts are generally unconscious, unintentional, and unrecognized by participants.  The remedy is increased government spending for research, an unlikely possibility these days.  This means journalists will be kept busy exposing the many problems that arise when scientists take industry funding.

*The documents collected by the New York Times

Additions:

Sep 6 2015

Another exposé of industry-funded scientists: this time, GMOs and organics

Today’s New York Times has another front-page (and on the inside, full-page) story on the food industry’s financial relationships with academic scientists.

The article describes how Monsanto funded scientists to lobby for GMOs in Washington (I will say more about this in a subsequent post).

But, as is clear from this report, the organic industry is doing much the same.

The Times based the story on e-mails it collected through open records law requests (the equivalent of Freedom of Information Act requests for federal documents).

And surprise!  I turn up in Charles Benbrook’s.  I learned this from checking Twitter yesterday.

Capture

I’m only on the B-list for influencing public opinion?  Alas.

It seems that Charles Benbrook, a strong proponent of organics (as am I), was working with (for?) the Organic Valley Cooperative on a public relations campaign to promote his organics-funded study demonstrating that organic milk has a healthier fatty acid profile than conventional milk.

I vaguely remember him contacting me about the study, but I didn’t write anything about it.  It appeared to be an industry-funded study with results favoring the sponsor’s interests—much as, in this case, I sympathize with those interests.

A few months later, I did write write about another conflicted organic study:

The study is not independently funded….This study is another example of how the outcome of sponsored research invariably favors the sponsor’s interests.  The paper says “the  [Sheepdrove] Trust  had  no  influence  on  the  design  and management of the  research  project  and  the  preparation  of publications  from the project,” but that’s exactly what studies funded by Coca-Cola say.  It’s an amazing coincidence how the results of sponsored studies almost invariably favor the sponsor’s interests.  And that’s true of results I like just as it is of results that I don’t like.

Benbrook has been criticized recently for not fully disclosing his ties to the organic industry.  Even if he had, disclosure is not enough.

The bottom line: Conflicted studies are conflicted, no matter who pays for them.

Documents: Charles Benbrook

Sep 3 2015

Five more industry-funded studies with predictable results. Score since March: 52:1

Energy flux: staying in energy balance at a high level is necessary to prevent weight gain for most people.  Gregory A Hand, Robin P Shook, James O Hill, Peter R Giacobbi, and Steven N Blair.   Expert Rev. Endocrinol. Metab.  Early online, 1–7 (2015)

  • Conclusion: Maintaining energy balance at a higher caloric intake and expenditure should be a more successful long-term strategy for weight maintenance than reduced consumption or extreme caloric restriction at a low level of energy expenditure (a low energy flux) and improve intervention effectiveness for sustainable methods for body weight stability. [Implication: eat more to lose weight?]
  • Funding: GA Hand received non-restricted research funding and travel grant from The Coca Cola Company and a travel grant from International Life Sciences Institute. RP Shook received a travel grant from the Coca Cola Company. JO Hill received research support from the Coca Cola Company and the American Beverage Association. JO Hill is on the advisory board for McDonalds, General Mills, Curves, Consumer Goods Association, Calorie Control Council, International Food Information Council and McCormick Science Institute. JO Hill is a consultant for Walt Disney, has equity in Gelesis and Active Planet and is on the Board of Directors for International Life Sciences Institute and Livewell Colarado. SN Blair is the principal investigator on projects supported by unrestricted research grants from The Coca Cola Company to the University of South Carolina.
  • Comment: Some of these investigators were among those highlighted in the New York Times article revealing Coca-Cola’s funding of research demonstrating that physical activity is more important than diet in weight maintenance.

Reducing obesity will require involvement of all sectors of society. James O. Hill, John C. Peters and Steven N. Blair. Obesity Volume 23, Issue 2, February 2015, Page: 255.

  • Conclusion: If the physical inactivity industry could commit to increasing physical activity by 78 calories a day per person, we would begin seeing some real success…we need innovative thinking, recognition that both food and physical activity are important, and open minds about how to engage all of society in making changes.
  • Disclosure: Dr. Hill reports personal fees from Coca-Cola, personal fees from McDonald’s, grants from American Beverage Association, personal fees from Walt Disney Company, personal fees from General Mills, personal fees from Calorie Control Council, other from International Life Sciences Institute, and other from Retrofit outside the submitted work. In addition, Dr. Hill has a patent Energy Gap issued. Dr. Blair reports grants from Technogym and grants from Coca-Cola. Dr. Peters has no competing interests to disclose.
  • Comment: same investigators as in previous example.

Instant Oatmeal Increases Satiety and Reduces Energy Intake Compared to a Ready-to-Eat Oat-Based Breakfast Cereal: A Randomized Crossover Trial. Candida J. Rebello MS, RD, William D. Johnson PhD, Corby K. Martin PhD, Hongmei Han MS, Yi-Fang Chu PhD, Nicolas Bordenave PhD, B. Jan Willem van Klinken MD, PhD, Marianne O’Shea PhD & Frank L. Greenway MD.  Journal of the American College of Nutrition Published online: 14 Aug 2015.  DOI:10.1080/07315724.2015.1032442

  • Conclusion: Oatmeal suppresses appetite, increases satiety, and reduces energy intake compared to the RTEC [ready-to-eat cereal].
  • Funding: The trial was funded by Quaker Oats Center of Excellence and PepsiCo R&D Nutrition….

Impact of equol-producing capacity and soy-isoflavone profiles of supplements on bone calcium retention in postmenopausal women: a randomized crossover trial.  Jessica W Pawlowski, Berdine R Martin, George P McCabe, Linda McCabe, George S Jackson, Munro Peacock, Stephen Barnes, and Connie M Weaver. Am J Clin Nutr September 2015 vol. 102 no. 3 695-703.

  • Conclusion: Soy isoflavones, although not as potent as risedronate [a drug used to treat osteoporosis], are effective bone-preserving agents in postmenopausal women regardless of their equol-producing status, and mixed isoflavones in their natural ratios are more effective than enriched genistein.  [Equol is an isoflavone produced by intestinal bacteria]
  • Conflicts: CMW is on the scientific advisory board of Pharmavite [the maker of SoyJoy]. SB has a US patent on the use of conjugated isoflavones and the prevention of osteoporosis.

Agave Inulin Supplementation Affects the Fecal Microbiota of Healthy Adults Participating in a Randomized, Double-Blind, Placebo-Controlled, Crossover TrialHannah D Holscher, Laura L Bauer, Vishnupriya Gourineni, Christine L Pelkman, George C Fahey, Jr., and Kelly S Swanson. J. Nutr. 2015; 145:2025-2032 doi:10.3945/jn.115.217331

  • Conclusions: Agave inulin supplementation shifted the gastrointestinal microbiota composition and activity in healthy adults. Further investigation is warranted to determine whether the observed changes translate into health benefits in human populations.  [Note: Agave inulin is a prebiotic, a fiber that can be metabolized by intestinal bacteria.  The study reports enrichment of fecal Bifidobacterium (the good kind)].
  • Funding: Supported in part by Global Nutrition R&D, Ingredion Incorporated, Bridgewater, NJ.  V Gourineni and CL Pelkman are employees of Global Nutrition R&D, Ingredion, Incorporated.  [Ingredion manufactures prebiotic fibers]

As always, please send examples, particularly of industry-funded studies that do not produce results in the sponsor’s interest.

Aug 26 2015

Five more industry-funded studies with expected results. Score: 47 to 1

The Inadmissibility of What We Eat in America and NHANES Dietary Data in Nutrition and Obesity Research and the Scientific Formulation of National Dietary Guidelines. Archer EPavela GLavie CJ. Mayo Clin Proc. 2015 Jul;90(7):911-26. doi: 10.1016/j.mayocp.2015.04.009. Epub 2015 Jun 9.

  • Conclusion: we conclude that M-BM [memory-based dietary assessment methods] data cannot be used to inform national dietary guidelines and that the continued funding of M-BMs constitutes an unscientific and major misuse of research resources.
  • Funding: National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health.
  • Potential Competing Interests: Dr Archer has received honoraria from the International Life Sciences Institute and The Coca Cola Company. Dr Lavie reports receiving consulting fees and speaking fees from The Coca-Cola Company….
  • Comment: This is part of what appears to be a concerted effort by Coca-Cola to discredit NHANES, the national survey of dietary intake and disease risk that consistently associates soda intake to poor health.

A high-protein breakfast prevents body fat gain, through reductions in daily intake and hunger, in “Breakfast skipping” adolescents.  Heather J. Leidy, Heather A. Hoertel, Steve M. Douglas, Kelly A. Higgins and Rebecca S. Shafer.  Obesity.  Article first published online: 4 AUG 2015.  DOI: 10.1002/oby.21185

  • Conclusions: The daily addition of a HP [high-protein] breakfast improved indices of weight management as illustrated by the prevention of body fat gain, voluntary reductions in daily intake, and reductions in daily hunger in breakfast skipping adolescents with overweight/obesity.
  • Funding: The Pork Checkoff supplied the funds to complete the study.
  • Disclosure: The authors declared no conflict of interest.
  • Comment: Industry-funded investigators typically state that funding does not introduce conflicts of interest.

Breakfasts Higher in Protein Increase Postprandial Energy Expenditure, Increase Fat Oxidation, and Reduce Hunger in Overweight Children from 8 to 12 Years of Age.  Jamie I Baum, Michelle Gray, and Ashley Binns.  J. Nutrition.  First published August 12, 2015, doi: 10.3945/jn.115.214551  J. Nutr. jn214551

  • Conclusion: This study indicates that breakfast macronutrient composition affects postprandial responses in both NW [normal weight] and OW [overweight] children. A PRO [protein-rich breakfast] increases postprandial EE [energy expendititure] and fat oxidation, reduces hunger, and increases satiety when compared with a carbohydrate-based breakfast.
  • Funding: Supported by a grant from the Egg Nutrition Center/American Egg Board, Chicago, IL. The Egg Nutrition Center/American Egg Board was not involved in the design, implementation, analysis, or interpretation of the data.
  • Author disclosures: JI Baum, M Gray, and A Binns, no conflicts of interest.
  • Comment: These industry-funded investigators also deny that funding introduces conflicts of interest.

The Effect of Breakfast vs. No Breakfast on Brain Activity in Adolescents when Performing Cognitive Tasks, as Assessed by fMRI [functional magnetic resonance imaging].  Jonathan Fulford1, Joanna L Varley2 and Craig A Williams.   Nutritional Neuroscience 2015 epub ahead of print.

  • Conclusion: Although no statistically significant (P > 0.05) improvement in task performance was determined, significantly higher activation was recorded in the frontal, premotor, and primary visual cortex areas in the breakfast trial relative to the fasting condition…Such a finding may have important implications in the examination of the role of diet, and specifically breakfast, in determining children’s performance within the school environment.
  • Funding: A grant was received of £18,678.08 from Kellogg Marketing & Sales Company (UK) Ltd to cover MRI scanning costs. Otherwise the research was conducted with the support of internal institutional funds and the authors received no other direct or indirect support, with no further competing interests.
  • Comment: Ordinarily I’m not concerned about food companies’ donating products to be tested but £18,678.08 seems noteworthy, especially since the only point of this study is to demonstrate that breakfast-eaters do better (higher brain activation even though no significant gain in task performance).

Suboptimal Serum α-Tocopherol Concentrations Observed among Younger Adults and Those Depending Exclusively upon Food Sources, NHANES 2003-2006. McBurney MI, Yu EA, Ciappio ED, Bird JK, Eggersdorfer M, Mehta S (2015). PLoS ONE 10(8): e0135510. doi:10.1371/journal.pone.0135510

  • Conclusion: The prevalence of inadequate vitamin E levels is significantly higher among non-users of dietary supplements…Our findings provide evidence that most Americans have serum α-tocopherol levels below 30 μmol/L. The EAR [Estimated Average Requirement], epidemiological and randomized controlled studies all indicate that maintaining a serum α-tocopherol concentration of 30 μmol/L may have beneficial effects on mortality, cognitive function and reproduction [Note: “may” indicates that what follows is speculative].
  • Funding: This statistical analysis of data collected by the Centers for Disease Control (CDC)…was supported by DSM Nutritional Products, a manufacturer of vitamin E. MM, EC, JB and ME are employees of DSM Nutritional Products. DSM Nutritional Products provided support in the form of salaries for authors MM, EC, JB, and ME and as an unencumbered gift to Cornell University that was used to support EY as a graduate research assistant.
  • Competing interests: This study was supported by DSM Nutritional Products, a manufacturer of vitamins, including vitamin E, for food, dietary supplement, and pharmaceutical use. MM, EC, JB, and ME are employees of DSM Nutritional Products.
  • Comment: Inadequate vitamin E in this study is defined as a serum level below a certain cut-point with uncertain clinical significance.  According to the Dietary Reference Intakes, clinical signs of vitamin E deficiency have not been observed in healthy populations.

Note: Since mid-March, I have posted 47 industry-funded studies with results favorable to food companies or trade associations, vs. 1 study with unfavorable results.

If you see industry-funded studies with results that must have made the sponsor unhappy, please send.

Aug 20 2015

Muhtar Kent, Coca-Cola’s CEO, and scientist Steven Blair respond to critics

Coca-Cola, in case you missed the furor over last week’s New York Times article, has a huge public relations problem.

The damage control begins today with Coke’s CEO’s op-ed in the Wall Street Journal:

Our company has been accused of shifting the debate to suggest that physical activity is the only solution to the obesity crisis. There also have been reports accusing us of deceiving the public about our support of scientific research…I am disappointed that some actions we have taken to fund scientific research and health and well-being programs have served only to create more confusion and mistrust. I know our company can do a better job engaging both the public-health and scientific communities—and we will.

By supporting research and nonprofit organizations, we seek to foster more science-based knowledge to better inform the debate about how best to deal with the obesity epidemic. We have never attempted to hide that. However, in the future we will act with even more transparency as we refocus our investments and our efforts on well-being.

He promises that the company will:

• Publish on our website a list of our efforts to reduce calories and market responsibly, along with a list of health and well-being partnerships and research activities we have funded in the past five years, which we will continue to update every six months.

• Charter and recruit an oversight committee of independent experts to advise and provide governance on company investments in academic research.

• Engage leading experts to explore future opportunities for our academic research investment and health and well-being initiatives.

Personally, I can’t wait to see the list of Coke-funded research activities.  Want to bet how many of those studies came out with results that Coca-Cola can use to claim that sugary drinks have no effect on obesity or type 2 diabetes?  I’d also like a count of the number of studies Coca-Cola has funded to cast doubt on the National Health and Nutrition Examination Survey, the country’s major dietary monitoring program, which has the annoying habit of linking sugary drinks to those conditions.

Mr. Kent ends his piece with this plea:

As we continue to learn, it is my hope that our critics will receive us with an open mind. 

Unless Coca-Cola stops pouring millions of dollars into fighting soda caps and taxes, stops targeting its marketing to minorities, and stops lobbying against public health measures to help people eat more healthfully, keeping Mr. Kent’s version of an open mind will be difficult. 

Steven Blair, one of the scientists involved in Coke-funded research, posted this statement today:

I have asked that my video addressing energy balance be taken down from the GEBN website. I regret that a statement I made in this video has been used by some to brand GEBN as a network focusing only on physical activity. This is not true and never has been true. From the beginning the mission of GEBN has been to study the science of energy balance which involves both diet and physical activity. GEBN has some of the top nutritionist experts in the world who have published research showing the importance of diet and in particular of soda consumption in causing obesity. My dismissal of diet as a cause of obesity did a disservice to their work. I hope many of you can relate to feeling so passionate about an issue that you say some things that you later regret. I believe that both diet and physical activity are important in obesity and that we must address both together to help people achieve healthy weights. I look forward to working with other GEBN researchers to do this.

James Hill, another of the scientists involved in this fiasco, also has issued a statement.  When it becomes public, I will post a link to it.

Additions, August 21

Aug 19 2015

Coca-Cola’s sponsorship of favorable research: the saga continues

When the New York Times published an article describing Coca-Cola’s financial sponsorship of university researchers who de-emphasize the role of sugary drinks in raising the risk of obesity and type 2 diabetes, it kicked up a storm.

USA Today’s editorial board said:

It isn’t that companies pay scientists to put out false research. It’s that companies fund the work of scientists who happen to be doing research that spurs consumers to look away from science that hurts corporate interests.

Soft drinks are far less dangerous than cigarettes, but GEBN’s website, tweets and videos come right out of Big Tobacco’s playbook, brought into the digital era. Its leaders have done research in the past under about $3 million in grants given to their universities.

USA Today also printed a response by a Coca-Cola spokesman:

A recent New York Times article created confusion about our support of research and non-profit organizations, stating we want people to think that only exercise matters and not diet — but nothing could be further from the truth. We have always operated under the fact that a healthy, balanced diet and regular exercise are key ingredients for a healthy lifestyle.

That said, we need to do a better job of being even more transparent about the research we fund, the non-profit organizations we support and the way we publicly share this information. And we will.

Yesterday, Senator Richard Blumenthal sent letters to the University of Colorado, West Virginia University, and the University of South Carolina urging them to  clarify the nature of the University’s relationship with projects funded by Coca-Cola and to review the academic integrity of such grant agreements.

I believe your university must determine whether this research is in effect promoting a predisposed and biased agenda, rather than reflecting the impartiality and objectively (sic) expected from a public academic institution.

Years of litigation with tobacco companies were necessary to fully expose the tragic public health consequences when companies lie about the hazards of the products they sell.  I am deeply concerned that we may force future generations to relive this history if corporate-sponsored studies devoid of scientific integrity are permitted once again to deceptively downplay and conceal the dangers of a product consumed on a mass scale.

Do not underestimate Senator Blumenthal’s ability to deal with food companies.  He, you may recall, was responsible for withdrawal in 2009 of the ill-conceived Smart Choices program during his stint as Connecticut’s attorney general.

I’m still waiting for the Global Calorie Balance Network to issue its promised statement.  Stay tuned.

Aug 17 2015

Coca-Cola’s partnership with cooperative scientists: a cartoonist’s take

Now cartoonists are producing their own interpretations of the revelations in the New York Times of Coca-Cola’s funding of scientists to argue that what you drink has far less to do with obesity than does how much you move.

In Sunday’s Times, Brian McFadden comes to this conclusion:
Capture2Here’s the entire strip

Capture1:

 

 

 

 

 

The Global Calorie Balance Network (GEBN) scientists say they will have a response to all the criticism (and now ridicule).

GEBN welcomes the opportunity to engage in a global debate and discussion on the science and application of energy balance to promote health and reduce chronic disease. GEBN also welcomes scrutiny and constructive criticism. We respect our critics and ask that they respect us in return. The recent media attention has raised important issues about the goal and mission of GEBN. We have taken these comments very seriously and are in the process of clarifying these issues here on our website. We will have that information available early this week.

I look forward to seeing it.

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