Currently browsing posts about: Cell-based

In the Brave New World we now live in, food technology has scored a big win.  Food Navigator has the story: How does a cultivated chicken cell line meet kosher standards?

In a world first, OU Kosher [The kosher certification division of the Orthodox Union] has determined that the chicken cell line of Israeli start-up SuperMeat meets kosher standards.

In another world first, the OU has recognised cultivated meat as kosher and meat.

How is this even possible?

The OU’s recognition comes after a series of halachic discussions (concerning Jewish religious laws) and scientific reviews. The latter focused on avian embryogenesis and stem cells, including the observation of the excision of embryonic stem cells from a fertilised chicken egg prior to the appearance of blood spots.

SuperMeat worked closely with the OU and eminent rabbis to identify the vital elements of the sourcing and process to make sure that it holds to the highest standards of Kashrut [dietary laws]….

SuperMeat obtains the stem cells from very early after fertilisation of the egg at a precise time before the emergence of blood spots eliminating the necessity for slaughter and ensuring there is no blood involved in the process….SuperMeat does not use FBS [fetal bovine serum] or any other animal components in its media or process.

In my book about pet food with Malden Nesheim, Feed Your Pet Right, we wrote a chapter on Kosher pet food (one of my favorites).

The kosher laws are based on biblical injunctions against eating two kinds of animals, those that do not ruminate and do not have completely cloven hooves (Leviticus 11:26), and young animals cooked in their mother’s milk (Deuteronomy 14:21).   Thus, they forbid such things as eating pork or mixing meat and dairy foods at the same meal.

The Passover celebration requires one additional restriction.   Jews are not allowed to have in the house or to consume any foods containing chametz—wheat, wheat starch, wheat gluten, barley, oats, oat fiber, and other grains—precisely the ingredients in many pet foods.

Given the multiple and not always identifiable sources of ingredients in pet foods, it is difficult to imagine how pet foods can conform to Jewish dietary laws at any time, let alone at Passover.

Can pet foods be kosher?  Is it acceptable to hold Passover seders for dogs and cats, as some do?  And must pet owners who observe Jewish dietary laws feed their animals according to such laws?  The answers are typically Talmudic: yes, and no.

Super Meat is not on the market yet.  But aren’t you relieved to know that when it is, the Orthodox Union has given its blessing to cell-cultured meat.

Brave New World indeed.

I don’t know about you but I’m riveted by what’s in the pipeline for cell cultured meat alternatives.   Here are some recent items I’ve been collecting.

Products under development

• Why the first mass-produced cultured meat product won’t be food: While in the long-term, Czech start-up Bene Meat Technologies plans to develop a cell-based steak product for human consumption, its short-term focus has pivoted to cultured pet food, CEO Roman Kříž tells FoodNavigator…. Read more
• Pork and microalgae cells combined in cultivated meat an ‘industry first’: Czech start-up Mewery claims to have developed the first prototype of cultivated meat based on microalgae. The company is already in talks with the Singapore Food Agency, founder Roman Lauš tells FoodNavigator…. Read more
• UK Scientist produce ‘world’s first’ 100% cultivated steak: UK-based scientists have produced the ‘world’s first’ steak fillet made from 100% cultivated meat. Read more

State of the industry

• Cultivated meat in focus at Tufts cellular ag innovation day: From bioreactor bottlenecks to a ‘global battle cry’ for government funding: It’s becoming increasingly clear that early projections about the speed with which cultivated meat might gain market share now seem pretty optimistic. But Rome wasn’t built in a day, and significant progress is being made to build the ecosystem needed to sustain a completely new industry, said key stakeholders at an event run by Tufts University on Thursday…. Read more
• Dissecting cultivated meat regulation part 2: What’s working in the US and Singapore, and what’s not?  Both the US and Singapore have seen cultivated meat products pass through their regulatory processes, yet the two governments approach novel foods in different ways. Which challenges and opportunities exist within these regulatory frameworks, and what impact could they have on Europe?… Read more

State of the techno-food scene

• Soylent acquired by Starco Brands as nutrition company shifts into its ‘natural next stage’: Soylent Nutrition is joining public company Starco Brands as part of an acquisition that will keep the plant-based food technology company operating as a separate unit under its current CEO Demir Vangelov.  As part of the transaction, Vangelov told TechCrunch that he will join Starco’s board and is getting shares in the new company, while himself and Soylent’s shareholders will become the largest single voting block in Starco. Other financial details were not disclosed.

Comment

Cell-based meat, meat-plus-algae, and pet food are not yet on the US market so it’s too early to see what they taste like and how well they will do.  I see these products as mostly about mergers, acquisitions, and generating lots of money for investors, which is why I included the Soylent event (Soylent is a nutrient supplement drink, but I put it in the same category of “techno-food”).

The International Political Economy Society (IPES) food section has just issued this report.

Its major thesis: alternative plant- or cell-based alternative meats are not the solution to world food problems.

As the report’s author, Phil Howard, explains in his Civil Eats editorial:

The hype around alternative proteins also diverts our attention away from solutions that are already working on the ground: shifting to diversified agroecological production systems, strengthening territorial food chains and markets, and building “food environments” which increase access to healthy and sustainable diets. These pathways respond holistically to challenges whose breadth and depth have been well-evidenced. They entail transformative behavioral and structural shifts. They require sustainable food system transitions, not merely a protein transition. Yet without a consolidated set of claims and claim-makers behind them, these pathways are systematically sidelined.

Don’t feel like reading the report?  Watch the video.

Other resources:

• Executive summary:  EN | FR | ES | P
• Full report EN | FR | ES | PT 
• Infosheet: Fake meat in the spotlight [EN] — This document is especially useful.

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In big news for the cell-cultured meat industry, the FDA has done its version of approving production of cellular chicken.

Here, in inimitable FDA-speak, is the agency’s essentially tacit approval of UPSIDE Foods, Inc’s cultured chicken cell material:

Based on the data and information presented…we have no questions at this time about UPSIDE’s conclusion that foods comprised of or containing cultured chicken cell material resulting from the production process defined in CCC [Cell Culture Consultation] 000002 are as safe as comparable foods2 produced by other methods. Furthermore, at this time we have not identified any information indicating that the production process as described in CCC 000002 would be expected to result in food that bears or contains any substance or microorganism that would adulterate the food.

And here’s what The Guardian has to say about this breakthrough.

With Singapore currently the only country in which lab-grown meat products are legally sold to consumers, the US approval could open the floodgates to a new food market that backers say is more efficient and environmentally friendly than traditional livestock farming.

That’s the big news.

But there’s more:

• Wilk makes yogurt using milk from cultivated cells: The Israeli company is the first to create a finished dairy product that has been produced by cells grown outside of an animal.
• Tracking the cell-based meat space: SuperMeat shows off a cultivated turkey prototype in time for Thanksgiving, and Steakholder Foods holds its first U.S. tasting.

Here are my questions:

• How does this stuff taste?
• Is it better than chicken?
• Will anyone want to eat it?
• If they do, can UPSIDE do this at scale?
• What will this chicken substitute cost?
• Is this really better for health and the environment?

I can’t wait to find out.

Tomorrow: What’s happening with plant-based meat alternatives.

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TODAY: Petaluma, 140 Kentucky, Copperfield’s Books, 7:00 p.m.  Information is here.

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Nature Food has an issue devoted largely to the topic of cell-based meat.

It is worth reading for getting an idea of where current thinking is on this issue, and also because of Phil Howard’s latest take on power on industry the cellular food category.

See his commentary article below.

• Editorial: Cellular agriculture and food systems priorities
• Feature: Cellular agriculture could be a game-changer or just another spot on the supermarket shelves, Karl Gruber
• Comment & Opinion

• Cultured meat needs a race to mission not a race to market, Dwayne Holmes, David Humbird, Jan Dutkiewicz, Yadira Tejeda-Saldana, Breanna Duffy et al.Comment
• A virtue-ethical approach to cultured meat, Carlo Alvaro
• Cultivated meat as a tool for fighting antimicrobial resistance, Eileen McNamara & Claire Bomkamp
• Thick and thin food justice approaches in the evaluation of cellular agriculture, Garrett M. Broad & Robert M. Chiles
• Cellular agriculture will reinforce power asymmetries in food systems, Philip H. Howard
• Challenges of assessing the environmental sustainability of cellular agriculture, Hanna L. Tuomisto
• The triple bottom line framework can connect people, planet and profit in cellular agriculture, Marianne Jane Ellis, Alexandra Sexton, Illtud Dunsford & Neil Stephens
• Transforming a 12,000-year-old technology, Bruce Friedrich

Research Highlight: The price is right for artificial meat, Anne Mullen

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For 30% off, go to www.ucpress.edu/9780520384156.  Use code 21W2240 at checkout.

None of this stuff is on the market yet, which is good or bad depending on how you look on it.  Maybe it’s just me, but these in-the-works products seem weird beyond belief.

Here’s what I’ve collected recently.

• Human milk the next challenge for cellular ag: Why not make human milk in a lab? As improbable and far-fetched — and maybe even blasphemous — as it may seem, scientists are working on doing just that. More than that, some are predicting the final product will be available in three or four years. “Startups are racing to reproduce milk in the lab,”… Continue Reading
• Opalia’s Animal-Free Milk Is Now One Step Closer to Supermarket Shelves:  Canadian foodtech startup hits key milestone on the road to commercialization by eliminating fetal bovine serum from its cell-based milk manufacturing.
• Cultivated meat, cell-cultured meat, lab-grown meat? Comments submitted to USDA over how best to label meat and poultry made from animal cells grown outside of animals reflect the challenge facing US regulators as they seek to nail down nomenclature in this nascent market as startups in the space edge closer to commercialization…. Read more
• The Bloody Secret Behind Lab-Grown Meat: Maybe we can’t have our steak and eat it guilt-free, too.
• Making cultivated meat ‘bleed’ with red algae: ‘Even cell-based meat looks pale; it will need our solution’:  New red microalgae discovered by Israeli start-up Yemoja adds ‘bloody’ juiciness to plant-based burgers and steaks, as well as cultivated meat products…. Read more

Even weirder, but perhaps more palatable, is making protein out of air.

• How Air Protein is making the journey from concept to product: The startup that makes carbon dioxide into a meat analog has been turning science and the need for more sustainability into something co-founder and CEO Lisa Dyson says can feed the world.

And here is a report from Food and Water Watch

• ‘Lab Meat’ Industry is Big Ag in Disguise:  New research shows that plant-based meat props up industrial farm system.

I’m seeing considerable confusion about the difference between cell-based and plant-based meat alternatives.

Cell-based products are not yet on the market, except in Singapore.  Plant-based products are everywhere, and I will deal with them separately tomorrow.

For an example of the confusion, Phil Howard’s op-ed in Civil Eats was first titled Giant Meat and Dairy Companies Are Dominating the Plant-Based Protein Market, but his informative diagram refers to cell-cultured meat and fish alternatives, those that start with cells of animal origin.  Civil Eats, ever careful, fixed the headline so it now reads, Op-Ed: Giant Meat and Dairy Companies Are Dominating the Plant-Based and Cellular Meat Market.  

Today, lets stick to cell-based, beginning with Joe Fassler‘s thoughtful analysis in The Counter: “Lab-grown meat is supposed to be inevitable. The science tells a different story.”

That science tells us:

• Manufacturers consistently miss targets for product release.
• Production costs are astronomical.
• Even if costs can be reduced, production volume can never match real meat.
• Producing cell-based meat to scale means keeping it free of contaminants (difficult, if not impossible)
• Fetal blood serum, a necessary ingredient, requires animals to be slaughtered.
• Cell culture facilities are resource-intensive.

In the meantime, here are some of the latest developments in regulation, image, and celebrity investment.

• USDA seeks comments on labeling cell-based meat: The notice, available in the Federal Register online, is a step toward establishing a regulatory framework for these products.
• Cell-based disruption: How many factories, and at what capacity, are required to supply 10% of the meat market?  If the cultivated meat industry were to set the ambitious target of supplying 10% of the global meat market, how much product would be required? How many factories, containing how many bioreactors, would need to be built? And where?… Read more
• Cell-based or cell-cultured: What’s the best name for next-gen seafood made from fish cells?
• With terminology ranging from cell-based to cell-cultured, cultivated, clean, and in vitro, how can consumer research help industry settle on one single term for next-gen seafood made from fish cells?… Read more
• Ad: How Aqua Cultured Foods plans to own the whole cut seafood analog space: Today Aqua Cultured Foods, a Chicago female-founded startup, announced their use of fermentation technology to create seafood alternatives with an incredibly realistic taste, texture, and nutritional profile…The company has developed whole-muscle cuts using biomass fermentation and a specific strain of fungi to deliver a high protein content comparable to cod, plus fiber and Omega-3s, without fat or cholesterol.
• Eat Just Raises $97 Million More to Fund Cultured Meat Production: The investment, which was part of a round announced in May that raised $170 million, came from new groups including Resilience Reserve, a venture capital fund, and existing backers like hedge fund UBS O’Connor and Graphene Ventures. This brings the round to $267 million, making it the largest ever for cultivated meat, which backers say will help to meet the world’s rising demand for animal products in a more humane and environmentally friendly way. Eat Just is also adding Dan Glickman, a former U.S. agriculture secretary, to its advisory board, and Jim Borel, a former executive at DuPont, to its board of directors.
• Leonardo DiCaprio invests in cultivated meat firms Mosa Meat and Aleph Farms:  Cultured meat innovators Mosa Meat and Aleph Farms have secured the backing of high-profile investor Leonardo DiCaprio, known for his Academy Award winning roles as well as his environmental activism…. Read more

And here’s a summary of the latest research on concentration and power in cell-based agriculure.

• Democratizing ownership and participation in the 4th Industrial Revolution: challenges and opportunities in cellular agriculture:  In this paper, we have sought to engage the nascent feld of cellular agriculture in conversation with the political economy of agriculture scholarship, namely, on the inescapable question of whether or not this emerging technology will further concentrate wealth and power in the global food system. Innovation without meaningful inclusion has led to inequality, distrust, environmental crises, and social disintegration, and the world’s biggest tech companies are well positioned to continue disrupting and absorbing traditional industries in the coming decades…Critically important and valuable innovation, including agroecological approaches to food production, also continues to come from non-industrial contexts.