by Marion Nestle

Currently browsing posts about: Salt

Jun 30 2025

Industry-funded study of the week: MSG of all things

The study: Maher, C. , Alcorn M., Childress A., Dawson J. A., and Galyean S.. 2025. “Increasing Vegetable Intake Using Monosodium Glutamate in a Randomized Controlled Trial: A Culinary Medicine Intervention.” Food Science & Nutrition 13, no. 6: e70441. 10.1002/fsn3.70441.

Purpose: “This study aimed to explore the effectiveness of monosodium glutamate (MSG) as a flavor enhancer in increasing vegetable intake compared to sodium chloride (NaCl) alone combined with a digital culinary medicine education program.”

Results: “The 50/50 NaCl/MSG group showed a mean increase in vegetable intake from 1.46 to 1.55 cups/day, while the NaCl group showed a decrease from 1.33 to 0.95 cups/day.”

Conclusion: “Although the differences in vegetable intake were not statistically significant, the findings suggest that MSG could enhance vegetable palatability and intake, aligning with the principles of culinary medicine.”

Conflicts of Interest: “The authors declare a conflict of interest due to Ajinomoto’s involvement in the funding and design of this study. Ajinomoto is a company that manufactures and sells MSG products. Their contribution included financial support and assistance in the study design, which could be perceived as influencing the outcomes of the research.”

Funding: “This study was funded by the American Society for Nutrition and its Foundation, grant number 1195905, and the APC [article processing charge] was funded by Ajinomoto.
Health & Nutrition North America Inc.”

Comment: The idea here is that if you sprinkle MSG rather than salt (NaCl) on your vegetables, they will taste better and you will eat more of them.  The study produced a non-significant result but is given a positive spin (“MSG could enhance…”).  The shocker here is the funding.  The authors say Ajinomoto funded it, but the funding statement mentions the American Society for Nutrition, an organization of nutrition researchers and clinicians to which I belong.  I had no idea ASN was funding research, let alone industry-funded research.  I have long been concerned about ASN’s industry partnerships, which I believe compromise the ability of the organization to issue advice on nutrition.  This is an old issue, but one that it seems time to bring up again.

Apr 21 2025

Industry-funded study of the week: Beef

Christopher Gardner writes me that the next time I need an example of an industry-funded study, I should take a look at this one.  Happy to.

The Study: A Mediterranean-Style Diet with Lean Beef Lowers Blood Pressure and Improves Vascular Function: Secondary Outcomes from a Randomized Crossover Trial.  Jennifer A Fleming, Kristina S Petersen, kup63@psu.edu, Penny M Kris-Etherton, David J Baer. Current Developments in Nutrition, Volume 9, Issue 4, 104573.

Objectives: “The aim was to evaluate the effects of a MED diet incorporating 0.5 oz./d (MED0.5), 2.5 oz./d (MED2.5) and 5.5 oz./d (MED5.5) of lean beef compared with an Average American diet (AAD) on vascular health [brachial and central blood pressure, pulse wave velocity (PWV), and augmentation index].”

Methods: “In random sequence order, participants consumed each test diet for 4 wk. Vascular outcomes were assessed at baseline and the end of each diet period.”

Results:  “PWV was lower following MED0.5…and MED2.5… compared with the AAD; PWV was nominally lower after the MED5.5 compared with the AAD…Central systolic blood pressure was lower following the MED0.5…and MED2.5…compared with the AAD…Brachial systolic and diastolic pressure were lower following all 3 MED diets compared with the AAD (P < 0.05).

Conclusions: Compared with an AAD, MED diets containing 0.5 and 2.5 oz./d of lean beef improved brachial and central systolic and diastolic blood pressure and arterial stiffness. Our findings suggest that a MED diet with ≤5.5 oz./d of lean beef does not adversely affect vascular function.

Funding: “This trial was funded by the National Cattlemen’s Beef Association, a contractor to the Beef Checkoff…Financial supporters had no role in the design and conduct of the study, collection, analysis, and interpretation of data, or preparation, review, or approval of the manuscript.

Conflict of interest: JAF received travel funds from the National Cattlemen’s Beef Association for giving presentations on this research. PMK-E and DJB received funding from the National Cattlemen’s Beef Association for the research reported in this article. KSP has received grants from the National Cattlemen’s Beef Association to conduct other research projects. KSP has also received honoraria from the National Cattlemen’s Beef Association for consulting work unrelated to the research presented in this paper.

Comment:  Professor Gardner noted that the AAD diet contained 3,500 mg sodium/day, whereas all three of the Mediterranean/beef diets had lower sodium (<2,300 mg/day).  Could reduced sodium have anything to do with the reduced blood pressure observed on the two diets containing lower amounts of beef (Med 0.5 and Med 2.5)?  The authors, alas do not discuss this point.  This makes this study appear to have been designed to demonstrate that eating beef does not adversely affect blood pressure.  Research on the effects of industry funding demonstrate that funders do not need to have a role in the design, conduct, etc of a study to exert influence.  Consciously or unconsciously, intentionally or unintentionally, funding recipients want to please their sponsors.  Studies of the effect of diet on blood pressure need to control for sodium intake.

Apr 16 2024

What is the FDA’s food regulatory role anyway?

The keynote address at the Consumer Federation of America’s annual food policy conference was given by the FDA’s new Deputy Commissioner for Human Foods, James “Jim” Jones.

He talked about his priorities and what he’s hoping the FDA will do.  Fine.

But in the Q and A, he was pushed repeatedly by Mike Jacobson (former head of CSPI) to say what the FDA would be doing to pressure the food industry to reduce salt in the food supply, something the FDA has promised to do for years with little progress.

In response, Jones said: “…I wouldn’t say pressure.  Pressure is not our statutory authority…isn’t to pressure….it is to help manage the food supply in a way that makes it healthier for Americans.”

Oh dear.

Pressuring the food industry most certainly is in the FDA’s authority.  I can think of lots of things the FDA has done that directly oppose food industry interests despite plenty of industry pushback: food labels in general and trans fat and sugar labeling in particular, restrictions on health claims, food safety regulations, and anything else the agency has done to force food companies to behave in the interest of public health.

Food companies will act in the public interest, only when they have to.  Jones’ statement, if that’s what he meant, is an alarming indication of agency capture.

The FDA is a regulatory agency and part of the Public Health Service.  It’s not supposed to win popularity contests.  It’s not supposed to be an arm of the food industry.

It’s supposed to take whatever tough steps are needed to keep the food supply safe and healthy so as to improve the overall health of Americans.

Yes, the FDA should be pressuring food companies about salt (and sugar, for that matter), and as strongly as possible.

Maybe I am misunderstanding what he said.  I hope so.

Here’s the video of the session.  Jacobson’s questions begin at 19:30.  Watch and decide for yourself.

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Oct 5 2023

Annals of marketing: is “not healthy” the latest trend?

My distant but dearly loved cousin, Michael Kravit, has scored again: “Not Healthy.”

According to the company’s website, these things are “Tasty purffs.  Five flavors.  No health claims…So unhealthy, I bought 15 bags for my family and friends…If you are worried about FFUPs being healthy, you’re on the wrong website.  Go eat some carrots! [Not a bad idea, this last one].

I managed to find the Nutrition Facts for one of them.  They have a lot of salt—320 mg per ounce.  The ingredient list:

Besides salty, how do these things taste?  If you can find some, please let me know.

While we are at it, my daughter sent this photo from the new It’s Sugar store on Market Street in San Francisco.

OK.  Let’s give these companies high marks for truth in advertising.  But do these represent the latest trend?

Caveat emptor.

 

Jan 24 2022

Marketing to dietitians: the benefits of MSG

Members of the Academy of Nutrition and Dietetics get SmartBriefs sent to their email addresses.

The subject line of this one: “A Surprising Sodium Reduction Tool for Your Clients

 

It is an advertisement; it even says so.  But it does not say who paid for it.

To find that out, you have to click on the subscribe or resource links.

Bingo!  Ajnomoto, the maker of MSG.

All of this is to convince dietitians to push MSG as a salt substitute:

 Extensive research has affirmed not only the ingredient’s safety, but its benefits for sodium reduction. Even the National Academies of Sciences, Engineering and Medicine has recognized MSG as a tool to reduce sodium in the food supply.

Is this a good or bad idea?  MSG still has sodium and its health effects remain under debate.

This kind of sponsorship should be disclosed, front and center, in ads like this, especially because much of the research demonstrating benefits of MSG was funded by guess which company.

The Academy of Nutrition and Dietetics should not permit ads that lack full disclosure.

Members: Complain to the Academy that you want these ads to stop.

Thanks to Jackie Bertoldo for alerting me to this one.

Dec 9 2021

Some recent articles on food product reformulation

What with all the pressure to make foods healthier, food manufacturers have been tweaking their products to reduce less healthful ingredients, especially salt and sugar.

Reformulated ultra-processed foods are still ultra-processed.

They raise the question: is a slightly healthier ultra-processed food a good choice?

These articles come from FoodNavigator-Asia.com, which tracks the food industry in that part of the world.

Oct 19 2021

Big news: FDA finally issues guidance on sodium reduction

On October 13, the FDA finally got around to finalizing its guidance for the food industry for voluntary, short-term (2.5 year) sodium reduction targets for lots of processed, packaged and prepared foods.

In a statement, the FDA says its new guidance

provides voluntary, short-term sodium reduction targets for food manufacturers, restaurants, and food service operators for approximately 160 categories of processed, packaged and prepared foods. The targets seek to decrease average sodium intake from approximately 3,400 milligrams (mg) to 3,000 mg per day—about a 12% reduction—over the next 2.5 years.

Reducing sodium has been on the FDA agenda for years.  It issued draft guidance in 2016.  On this, it received about 200 comments.  

The FDA’s idea for this first target is to reduce average daily sodium intake by about 12%—from approximately 3,400 milligrams (mg) to 3,000 mg per day—in 2.5 years.

This is still higher than the recommended 2300 mg.  Why so limited?

Politics, of course.

The FDA believes

  • These targets are feasible.
  • Gradual reduction will accustom people to lower sodium intake.
  • Food companies might be willing to do this.

A quick review of the basics:

  • Salt is 40% sodium (2300 mg sodium means about 6 grams of salt or 1.5 teaspoons).
  • High salt diets are strongly associated with high blood pressure and stroke.
  • We require less than 500 mg sodium a day; average diets are greatly in excess.
  • Most salt in the diet comes from pre-prepared foods (70%); 20% is added at the table; 10% is innate in foods.
  • The taste for high-salt is acquired; the more salt you eat, the more salt it takes to make foods taste right.
  • For people used to high-salt diets, low-salt makes food taste bland.  It takes about three weeks to get used to low-salt.
  • Once accustomed to low-salt, typical levels of salt make food taste too salty.

Thus, the FDA’s strategy is to gradually accustom people to lower salt intake.

The guidance is voluntary: “This voluntary, iterative approach is similar to approaches successfully implemented in other countries.”

By other countries, the FDA must mean Great Britain.  The UK did a big voluntary salt reduction campaign some years ago and got enough buy in from food companies to see a real difference in salt intake and blood pressure.

When the government changed and laid off the pressure, companies put back most of the salt (not all though). That history is here.

So this could work if food companies cooperate.  Presumably, the FDA will assess the results of this voluntary effort in 2.5 years.

The stick?  The implied threat of mandatory reductions if the voluntary ones don’t work.

2.5 years is a long time to wait for voluntary compliance.

My view

  • These should have been mandatory to begin with.
  • The target levels should be lower.
  • The time scale should be faster.

Other than that, the FDA’s plan could be a useful first step.  We shall see.

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Jun 24 2021

Do product reformulation strategies make any nutritional difference?

That’s my question when I see what food companies are trying to do to reduce the content of sugar and salt in their ultra-processed junk food products.

To put it another way, does making an ultra-processed food or beverage slightly better for you convert it to a good choice?

We can argue about this, but companies really are trying hard, as this collection of articles from FoodNavigator.com indicates.

Special Edition: Nutrition and reformulation strategies

Most shoppers say they want to reduce consumption of products that are high in fat, salt and sugar. But many struggle to cut HFSS foods and beverages from their diets and reformulation efforts often face the headwind of perceived quality issues. Meanwhile, the fortified food market in Europe is expected to see a CAGR of 5.2% through to 2025. While reformulation efforts take out the ‘baddies’ is there also an opportunity to add positive nutrients through fortification?