The President of the United States says Coke should switch from high fructose corn syrup (HFCS) to cane sugar.

My response: this is nutritionally hilarious.

• HFCS is glucose and fructose separated in liquid form.
• Cane sugar (sucrose) is glucose and fructose bonded, but quickly split (so is beet sugar, but the Presudent is not mentioning it).
• Both HFCS and cane sugar are sugar(s).  Both provide about 4 calories per gram.
• There may be people who can taste the difference, but when Coke found that nobody could tell the difference, it switched from sucrose to HFCS.

I’ve written about this previously, most recently in 2014: HFCS politics, continued. Endlessly.

Yes, HFCS is derived from genetically modified corn, but that doesn’t change the basic biochemistry, taste, or health effect.

Note: A 12-ounce Coke has 39 grams of either one.  It doesn’t matter which sugar is used; it’s too much to be consumed at one time.

At the time Coke switched to HFCS, it was much cheaper.  It is still cheapter but less so (because half of corn production is used to produce ethanol).

It will cost Coke more to replace HFCS with cane sugar or even beet sugar (which is identical to cane sugar).  So Coke is not exactly committing to doing this.

As Reuters reports, the switch would raise prices for consumers and be tough on US farmers too.

On this issue, I have to agree for once with the Corn Refiners Association.

This is one of those issues it will be enormous fun to watch.  Stay tuned.

A new study says eating saffron will improve your mood.  Guess who funded it.

The Study: Lopresti AL, Smith SJ, Marx W, Díez-Municio M, Morán-Valero MI. An Examination into the Effects of a Saffron Extract (Affron) on Mood and General Wellbeing in Adults Experiencing Low Mood: A Randomized, Double-Blind, Placebo-Controlled Trial. J Nutr. 2025 Jul;155(7):2300-2311. doi: 10.1016/j.tjnut.2025.05.024. Epub 2025 May 23. PMID: 40414301.

Background: Saffron, derived from the stigmas of the Crocus sativus flower, has been shown in previous trials to have antidepressant effects in clinically diagnosed adults. However, the recruitment of small sample sizes, short treatment periods, and variability in the quality of studies have negatively impacted the strength of conclusions.

Objectives: The purpose of this 2-arm, 12-wk, parallel-group, randomized, double-blind, placebo-controlled trial was to examine the effects of supplementation with a saffron extract (Affron) on mood and sleep in adults experiencing subclinical depressive symptoms.

Methods: Two hundred and two adults aged 18-70 with depressive symptoms were supplemented with 28 mg saffron daily or a placebo.

Results: Compared to the placebo, saffron was associated with greater improvements in the Depression, Anxiety, and Stress scale….However, in the other secondary outcomes, there was no evidence of between-group differences.

Conclusions: This study…provides evidence supporting the beneficial effects of 3 mo of saffron supplementation on depressive symptoms in adults. Large placebo responses were evident in this study, which require consideration in future trials.

Funding: We thank Pharmactive Biotech Products, SLU, for funding the project and supplying the investigational products used for this
study.

Conflict of interest: ALL is the Managing Director of Clinical Research Australia, a contract research organization that receives research funding rom nutraceutical companies… SJS is an employee of Clinical Research Australia. WM has received funding and/or attended events funded by Cobram Estate Pty. Ltd. and Bega Dairy and Drinks Pty. Ltd…MD-M and MIM-V are employees of the study sponsor, Pharmactive
Biotech Products SLU.

Comment:  Let’s hear it for placebo responses!  Saffron is an extremely expensive spice usually used in pinch amounts.  If it’s hard for you to imagine that it could do anything to affect depression, subclinical depression yet, there’s a good reason for that—although saffron makes food taste delicious and that alone is a mood-improver.  But this study was done with a supplement, not the expensive spice.  Overall, this is a study done under contract from the supplement’s manufacturer by employees of the manufacturer.  As such, it is explicitly marketing research.  The interpretation of this study is predictable if you know who funded it.  The title of the study alone should generate the question: Who funded this?

NIH, and agency of the Department of Health and Human Services under Robert F. Kennedy Jr, has issued its strategic plan for nutrition research for the next five years.

The Table of Contents states the goals and research objectives.

The goals:

1. Advance Science
2. Support the generation of evidence to address priority diet, nutrition, and health outcomes
3. Build Capacity and Strengthen the Field of Nutrition Science
4. Foster Stewardship, Collaboration, Transparency, and Accountability in Nutrition Science Research

I went right to #2.  Its impact objectives:

1. Improve the Approaches and the Precision of Methods to Assess the Determinants of Malnutrition
2. Support the Generation of Evidence to Enhance Nutrition Regulatory Science

Oops.  Nothing about chronic disease?  Where is the MAHA agenda in this?

On closer look, the report mentions chronic disease 8 times.  It recognizes the problem, stating that

food systems and the food environment…are critical factors affecting consumer choices; dietary patterns; and, ultimately, health. Using this framework, ONR [Office of Nutrition Research]…will address critical components of the nutritional ecology—such as the shaping and impact of consumer attitudes, beliefs, and behaviors regarding food systems—and consider key questions to identify knowledge gaps in nutrition science that have direct bearing on diet-related chronic diseases….topical areas may include:

• Food production
• Food distribution and marketing
• Food delivery
• Food Is Medicine interventions
• Brain–body interactions
• Cooking and nutrition education
• Personalized and precision nutrition interventions

Ah yes, precision nutrition (targeting diets to specific individual genetic factors).

Identifying factors that predict inter- and intra-individual variability will likely decrease the burden of diet-related
chronic diseases and conditions and will also offer ways to tailor interventions for individuals and populations. [Goal 1, research objective 2]

The plan is organized around a unifying vision of precision nutrition research and includes four strategic goals and five crosscutting research areas. These opportunities complement and enhance ongoing research efforts across NIH to improve health and to prevent or treat diseases and conditions affected by nutrition. [Box 1]

The strategic goals are organized around four questions:

• What do we eat, and how does it affect us?
• What and when should we eat?
• How does what we eat promote health across our lifespan?
• How can we improve the use of food as medicine?

These are good questions, but to me they seem like public health questions.  It’s hard for me to imagine how they could be answered through precision nutrition.

I look forward to finding out how NIH plans to do this.

I wanted to know more when I read this article summary:

Food fraud: Spotlight on the most heavily targeted food products: New research shows the same foods – from beverages to dairy – are impacted by food fraud year after year… Read more

And what are they?

What kind of fraud are they talking about?

Leaning on FoodChain ID data, the report shows that botanical and animal origin fraud were the most prevalent in 2024 and over the last 10 years, with dilution also a major issue. In 2024, the use of non-standard substances was classed in third. “Botanical and animal origin fraud were the most reported type of food fraud in 2024, followed by use of non-food substance and dilution…of these frauds, using non-food substances in food has the potential to do the most harm as seen in the Sudan dyes in chilli powder and melamine in infant formula incidents.”

Shades of the early days of food adulteration.  It’s still happening, apparently.

Sugar has long been thought to increase risks for type 2 diabetes, but whether it really does has not been easy to prove and is still a matter of debate.

A new study suggests one reason why.  It distinguishes between the effects of sugar in beverages (increased risk) and foods (no increased risk).

The study: Dietary Sugar Intake and Incident Type 2 Diabetes Risk: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies.

Method: The study analyed prospective cohort studies reporting relative measures of incident T2D [type 2 diabetes] risk by categories of dietary sugar (total, free, added, fructose, sucrose) or 2 beverage sources (non-diet sugar-sweetened beverages [SSBs], fruit juice) in healthy adults.

Results: 

• Each additional serving of SSB and fruit juice was associated with a higher risk of T2D.
• In contrast, 20 g/d intakes of total sugar and sucrose were inversely associated with T2D.
• No associations were found for added sugar…or fructose.

The figure shows the effect of 20 g/d sugar intake on T2D risk, in comparison to typical doses of SSB and fruit juice.

A) shows the bar plot illustrating the summary effect of a 20 g/d intake for different sugar types on risk of T2D.

B) compares these doses to typical servings sizes per day of SSBs (39 g/d) and fruit juice (23.3 g/d).

Conclusion: These findings suggest that dietary sugar consumed as a beverage (SSB and fruit juice) is associated with incident T2D risk. The results do not support the common assumption that dietary sugar (i.e., total sugar and sucrose), irrespective of type and amount, is consistently associated with increased T2D risk.

Comment: Sugar is still nutritionally empty, causes tooth decay(especially if water is unfluoridated), and is best consumed in small amounts.  But if this finding holds up, the moral is clear:  Don’t drink your calories.

Michael Jacobson, founder of CSPI and now working on developing a National Food Museum in Washington, DC has issued press release and a graph-filled report analyzing changes in the U.S. diet since 1975.

He calls the report, “Opening the 1975 Food Time Capsule – Diet, Health, & Food Industry.”

From the press release:

And the food industry has gotten a lot more concentrated:

• In 1975, the top 20 grocers sold 40 percent of retail food. Now, just four companies (Walmart, Costco, Kroger, Ahold Delhaize) control 65 percent of the market.
• The market shares of the top four beef, pork, and poultry processors roughly doubled over the last 50 years.

Meanwhile, food prices (adjusted for inflation) have gone up, down, or sideways. For instance, milk costs half as much as 50 years ago, while ground beef has stayed the same. Overall, consumers are spending just 11 percent of their disposable income on food now compared to 13 percent in 1975.

From the report:

Lots of fun information here!

I particularly like it because I cover these changes and lots of others in my forthcoming book What to Eat Now.  to be published on November 11 this year.

Thanks to Matthew Kadey for this one.

Editors of Creative Homeowner.  Ultimate Guide to Planting & Growing Vegetables at Home: Expert Advice for Planting, Growing, and Controlling Pests for Over 70 Vegetables. Creative Homeowner, 2025.

Part of my blurb ended up on the front cover:

Ultimate Guide is just that–an indispensable source of wisdom and deeply practical advice for any vegetable grower.  Professionals as well as beginners will learn much on every page.  This book is a treasure.

I have a garden on the terrace of my New York apartment (I’m currently harvesting the last of the blueberries and raspberries), so was especially happy to be sent this book.  Here are some excerpts.

From the section titled, Grow What You Like

Your vegetable garden is all about providing you with great things to eat, so start by listing all the fruits and vegetables that you and your family will enjoy…The reality is that if you are putting your precious time into growing something, it should be a vegetable that’s a staple in your kitchen.

From: Using compost

Hungry plants such as potatoes and members of the brassica (cabbage) family make the best se of compost or worm compost. Apply before sowing or planting in spring and early summer. Winter brassicas such as Brussels sprouts and sprouting broccoli can benefit from a second application in July or August. In poorer soils, vegetables such as squash, Swiss chard, onions, beans, and beets will also benefit from the application of compost…Worms might not be the most beautiful of creatures, but they are exceptionally effective at producing rich compost.

From: Dealing with garden critters

For any gardener who has experienced the devastating effects of a rabbit in their garden, chicken wire (also known as poultry netting) is an absolute must…It is important to use netting with 1″ (2.5cm) holes and a width of 48″ (121.9cm)…If you follow these instructions to install chicken wire around the entire area to be protected, the crops will be completely safe from attacks by rabbits

From: Never let weeds get out of hand

The trick is to dig weeds out of beds and aisles before they go to seed or spread a network of perennial roots. But keep in mind that every time you disturb the soil, you expose a few
more dormant weed seeds. Take a dandelion digger with you on your weed safaris. With its small, V-pointed, long-shank blade you can cut roots deep in the soil and pull the weed out with little disturbance. Throw weeds into your compost pile. If you leave them where they pulled, they may take root and regrow…If you pull, dig out, or hoe weeds as soon as you see
them, and don’t allow them to go to seed, you will soon reduce the number that sprout in  your garden. While weeds among your vegetables might attract beneficial insects, weeds compete strongly with vegetables for plant nutrients and soil moisture.