by Marion Nestle

Search results: journal nature

Feb 23 2021

Are frozen foods the cause of the Covid-19 pandemic?

I can’t believe we are even talking about this, but the FDA, USDA, and CDC have just issued a rare joint statement addressing it [my emphases throughout].

After more than a year since the coronavirus disease 2019 (COVID-19) outbreak was declared a global health emergency, the U.S. Department of Agriculture, the U.S. Food and Drug Administration and the U.S. Centers for Disease Control and Prevention continue to underscore that there is no credible evidence of food or food packaging associated with or as a likely source of viral transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus causing COVID-19.

This, no doubt, is in response to statements from the World Health Organization team that visited Wuhan to determine the source of the virus causing Covid-19.  This team has not yet issued its report, but members of the team have talked to reporters.

Nature, for example, reports:

The researchers largely discounted the controversial theory that the virus accidentally leaked from a laboratory, and suggested that SARS-CoV-2 probably first passed to people from an animal — already a leading hypothesis among researchers. But the team also offered two hypotheses promoted by the Chinese government and media: that the virus, or its most recent ancestor, might have come from an animal outside China, and that once it was circulating in people, it could have spread on frozen wildlife and other cold packaged goods….Dominic Dwyer, a medical virologist at New South Wales Health Pathology in Sydney, Australia, and a member of the WHO team, says there is some evidence that the coronavirus could have spread on contaminated fish and meat at Chinese markets, and more details will be included in the written report.

According to the Wall Street Journal,

Beijing has blamed frozen-food imports as one cause of a string of recent outbreaks, and it has introduced mandatory testing and disinfection of foreign goods, saying it found traces of the virus on packaging of products including American pork, Saudi shrimp and Brazilian beef.

This idea has had a profound effect on sales of frozen foods.

Everyone seems to agree that there are four key hypotheses to explain the origin of this particular Coronavirus: 

  • Direct animal vector
  • Intermediary animal vector
  • Laboratory accident
  • Frozen food products,

The team could not identify a specific animal vector, dismissed the idea of a laboratory accident, but left open the possibility of frozen food.

The frozen food idea was suggested by the Chinese.

Several top Chinese scientists have further suggested that the Sars-CoV-2 virus that causes the Covid-19 disease may have arrived in the Huanan Seafood Wholesale Market in Wuhan city, the location of the world‘s first known outbreak, via frozen food imports, or what’s referred to as cold-chain transmission.

The WHO team’s report is considered a public relations win for the Chinese.

The W.H.O. team opened the door to a theory embraced by Chinese officials, saying it was possible the virus might have spread to humans through shipments of frozen food, an idea that has gained little traction with scientists outside China.… The virus was circulating in Wuhan several weeks before it appeared at the Huanan Seafood Wholesale Market, where some of the earliest clusters were initially reported, the experts said. It most likely emerged in bats and spread to humans through another small mammal, though the experts said they have not been able to identify the species.

The team, as I mentioned, considered a laboratory origin unlikely.

The team called for further investigation into the possibility of “cold chain” transmission, referring to the transport and trade of frozen food.

US Federal agencies don’t believe this for a minute; hence, their joint statement.

So if frozen foods are not at fault, and no animal vector can be conclusively identified, that leaves us with the dismissed-out-of-hand laboratory origin.

So what’s up with that?  Wuhan, where the pandemic started, happens to be the site of a laboratory that works on Coronaviruses.  

Why does the origin of the pandemic matter?  

  • If we don’t know how this one happened, how can we take steps to prevent the next one?
  • And it matters a lot to the makers of frozen foods.
Jan 6 2021

Trump’s Covid stimulus bill: how it affects food and nutrition

I’m trying to make sense of the new $900 billion stimulus bill signed by President Trump a week or so ago.  This is not easy to do; it’s 5500 pages of government-speak.

The bill has $26 billion for food and nutrition, of which half goes to Big Ag (sigh) and the other half to food assistance (good, but not enough).

Why the sigh for farm aid?  Here’s what the accounting looks like:

Big Agriculture: $13 billion on top of what else it got in 2020

  • $32 billion from the initial CARES Act
  • $4 billion as compensation for the trade war with China
  • $16 billion from the normal Farm Bill subsidies
  • $13 billion from the new stimulus package ($1.5 billion is for buying food products, including seafood)

Small Ag:  $225 million (not billion) for growers of specialty crops like fruits, nuts and vegetables.

SNAP: a 15% expansion through June 2021.  This will mean a lot to recipients, but it’s still not enough.

SNAP Fruit and vegetable incentives: $75 million (not billion) for the Gus Schumacher Nutrition Incentive Program,

Pandemic-EBT: this authorizes extra benefits for families who have kids normally getting subsidized school meals (but this has been delayed)

Food banks: $400 million (not billion) for the Emergency Food Assistance Program, $400 million (not billion) for milk,

Disadvantaged, veteran, and beginning farmers: $75 million (not billion)

International Food Assistance: $1.74 billion for Food for Peace grants and $230 million for the McGovern-Dole International Food for Education and Child Nutrition program (note that this is the most the US has ever spent for these programs.

Pet foods: By congressional directive:

FDA is directed to provide an update on the investigation it is undertaking regarding canine dilated cardiomyopathy (DCM) and the manner in which it has released information to the public. The update shall include: the case definition FDA uses to include or exclude cases and the scientific work ongoing at the agency and with collaborating partners for identifying a causation of DCM; how FDA distinguishes cases of DCM due to genetic predisposition in certain breeds; how the agency plans to work with pet food companies and the veterinary cardiology community during the investigation; and the timing and nature of any future public reporting.

PFAS (Per- and polyfluoroalkyl) chemicals in food packaging: “directs FDA to review any new scientific information pertaining to PF AS chemicals and determine whether food packaging continues to meet the safety standards of a reasonable certainty of no harm under intended conditions of use.”

Restaurants: they get whatever they can out of the $284 billion Paycheck Protection Program.  The trade association for independent restaurants points out that this is nowhere near enough.  Even the Wall Street Journal says restaurants need help; their situation is bleak.

Business lunches: the full cost can now be deducted as a business expense, but nobody expects this to help restaurants much.

There is undoubtedly more, but that’s enough for now.

Politico has done a great job of covering these provisions, but is behind a paywall.  The Counter also has an especially good summary..

Dec 9 2019

Industry-funded study of the week: a live-forever dietary supplement

When I saw this ad in last Thursday’s New York Times, I immediately clipped it out.

What is this?

It is an ad for a dietary supplement, Telos95, with a classic structure/function claim (a type invented for dietary supplements of less-than-established efficacy): “telomere & DNA chromosome health support—-telomere lengthening and lowering cellular age in just 6 months.”

Telos95 is the only plant-based dietary supplement that aids in the chromosome stability during the process of cell replication.  It’s vital that normal cell replicative senescence takes place, so the cells divide in a healthy state and telomeres remain at the same length or lengthen, which biologically ensures a health centrosome matrix and repetitive nucleotide sequence at each end of the chromosome.

Got that?

What’s with telomeres?

All of this refers to work that got a Nobel Prize for Elizabeth Blackburn, Carol Greider, and Jack Szostak in 2009.  They showed that telomeres, caps on the end of chromosomes, protect chromosomes from degradation.  Shorter telomeres are associated with cell aging.

What got my attention in this ad was its report of a 2018 clinical trial finding that this supplement reduced cellular age by more than 7 years.

Really?  I had some immediate questions.

What’s in the supplement? 

The ad doesn’t say anything other than “all natural food grade polyphenols.”  But I managed to find a Supplement Facts Label online.

Highly purified polyphenols extracted from grape and olive leaves?

These, by the way, cost about $100 for 30 capsules.

Whatever.

What’s the study? 

I was able to find it online: A randomized-controlled clinical study of Telos95® , a novel antioxidative dietary supplement, on the shortening of telomere length in healthy volunteers  

It’s in a journal I’ve never heard of previously: HealthMed, published in Bosnia and Herzogovina

The report of the study starts out rather peculiarly:

The objective of this study was to determine the deodorant effectiveness of a dietary supplement to halt the shortening of telomere length as measured through blood samples before and after product use.

Deodorant?  Maybe something is lost in translation here?

Who paid for the study?

The published paper doesn’t say.  It does, however, refer to a Sponsor responsible for the study’s protocols, safety evaluation of the products, and safety indemnification of Princeton Consumer Research Corp (PCR), the group that carried out the study.

PCR’s website, by the way, states that “PRINCETON CONSUMER RESEARCH IS NOT AFFILIATED IN ANY WAY TO PRINCETON UNIVERSITY”.  Whew.

PCR’s press release credits Certified Nutritionals as behind the study.

What is this all about?

The Daily Beast did an investigative report on something similar a couple of years ago.

Obviously, this is about selling a supplement made from rice at profits so great that Longevity by Nature can afford a full-page ad in the Times (these used to run in the $80,000 range, if not more).

It is also about the use of industry-sponsored research to sell products: the sponsored study –> press release –> huge advertisement –> increased product sales.

Will this product keep your telomeres from shortening?  If only.

Aug 27 2019

Corporations will focus on social values? Really?

The Business Roundtable’s Statement (and see B Corporation Statement below)

The Business Roundtable, an organization of corporations, issued a statement last week—in a two-page advertisement with all the signatures in the Wall Street Journal, no less—that got this New York Times headline: Shareholder Value Is No Longer Everything, Top C.E.O.s Say.

What?  This is some kind of joke, right?

I’ve been arguing for years that the Shareholder Value Movement, which forced corporations to single-mindedly focus on maximizing profits at the expense of every other societal value—attention to the welfare of workers, farm animals, public health, environmental protection—is responsible for just about everything that is wrong with our food system.

Corporations are now saying that they are committing to change that?

The Business Roundtable’s press release says that it is redefining the purpose of corporations to promote an economy that serves all Americans—customers, employees, suppliers, communities, and shareholders.   Here is its website with all the commitment info.

Its statement, signed by nearly 200 corporations, commits them to [with my comments]:

  • Delivering value to our customers [they aren’t already doing this?].
  • Investing in our employees. This starts with compensating them fairly and providing important benefits [this would indeed be a groundbreaking improvement].
  • Dealing fairly and ethically with our suppliers [they weren’t doing this either?].
  • Supporting the communities in which we work [another excellent idea].
  • Generating long-term value for shareholders [isn’t this what they’ve been doing to the detriment of everything else?]

This sounds good, but how do they plan to solve the central dilemma?  How do they intend to pay workers decent wages, improve the communities in which they operate, and stop damaging the environment—and still maximize benefits for shareholders?

No surprise, they don’t say.

Also, as the Times noted,

There was no mention at the Roundtable of curbing executive compensation, a lightning-rod topic when the highest-paid 100 chief executives make 254 times the salary of an employee receiving the median pay at their company. And hardly a week goes by without a major company getting drawn into a contentious political debate. As consumers and employees hold companies to higher ethical standards, big brands increasingly have to defend their positions on worker pay, guns, immigration, President Trump and more.

I looked for food corporations among the signers (sorry if I missed any):

  • Aramark
  • Bayer (it owns Monsanto)
  • Coca-Cola
  • Land O’Lakes
  • PepsiCo
  • Procter & Gamble
  • Walmart

This is a small list.  Where, for example, are Mars, Nestlé, and Unilever?

I see this as flat out public relations, a response to increasing public distrust of corporate America and demands for corporate accountability.

If the signers mean business, let’s see them deal with workers’ wages right away.

Otherwise, I’m not holding my breath

The B Corporation Statement

And here’s more.  Sunday’s New York Times carried this advertisement from Certified B Corporations “meeting the highest standards of verified social and environmental performance, public transparency, and legal accountability to balance profit and purpose.”

The ad is addressed to Business Rountable CEOs.

We are part of a community of Certified B Corporations who are walking the walk of stakeholder capitalism…We operate with a better model of corporate governance—benefit corporate governance—which gives us, and could give you, a way to combat short-termism and the freedom to make decisions to balance profit and purpose.

Among its food company signers are Ben & Jerry’s, Cabot Creamery Cooperative, Danone North America, King Arthur Flour, Sir Kensington’s, Stonyfield Organic, and Stumptown Coffee (there are others, as well).

I read this as a challenge: if the Business Rountable CEOs are serious about ensuring as B Corporations do, that “the purpose of capitalism is to work for everyone and for the long term,” why don’t they start by becoming B Corporations?

Until they do, the Business Roundtable statement is smoke and mirrors, to distract us from the damage the corporations are doing to our society and to our democratic institutions.

Aug 16 2019

The latest on CBD edibles: sales booming, but no science or regulation

I’m watching what’s happening with Cannabis edibles with much interest.  Sales are booming.  Regulators are stymied.  Regulation is virtually absent—nobody seems to know how—and science, alas, hardly exists.

BakeryandSnacks.com fills the information gap with an Editor’s Spotlight on CBD [cannabidiol]-Infused Snacks, from the business perspective, as always.

And I’ve collected a few more from other sources.

And here’s a free White Paper on Cannabis edibles—a cross-industry analysis.

Tags:
Aug 5 2019

Industry-funded study of the week: “probiotic” weight-loss supplement

I spotted some tweets about this study from Washington Post writer Tamar Haspel, who has a sharp eye for this sort of thing.  Her first tweet said:

Her second tweet explained the problem:

So of course I had to look up the study.  It’s not one I would ordinarily have noticed because its title does not use the word “probiotic,” which typically refers to the live bacteria (in yogurt, for example).  The evidence for benefits of probiotics is iffy, so this study raises lots of questions.

Let’s take a look at it:

The Study:  Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study. Depommier C, et al.  Nature Medicine (2019

Conclusion: I’ve left out the statistics to make this easier to read:  “Compared to placebo, pasteurized A. muciniphila improved insulin sensitivity…, and reduced insulinemia…and plasma total cholesterol…. Pasteurized A. muciniphila supplementation slightly decreased body weight…compared to the placebo group, and fat mass…and hip circumference…compared to baseline….In conclusion, this proof-of-concept study…shows that the intervention was safe and well tolerated and that supplementation with A. muciniphila improves several metabolic parameters.”

Competing interests:  Five of the authors “are inventors of patent applications…filed with [patent offices in at least 12 countries]…dealing with the use of A. muciniphila and its components in the context of obesity and related disorders.” Two of the authors are cofounders of A-Mansia Biotech S.A., a Belgian company that sells A. muciniphila supplements, presumably as weight-loss supplements.

Comment: As Haspel points out, the subjects in this study were given either (a) live bacteria, (b) Pasteurized (and, therefore, mostly dead) bacteria, or (c) a placebo.  The Pasteurized ones were associated with metabolic benefits and weight loss.  Pasteurization is what gets done to milk to kill most—not all—of the living bacteria it contains.  In this study, Pasteurized bacteria had the same effect on the microbiome as the unpasteurized.  The point of the study was to show that the Pasteurized supplement would induce weight loss; the observed loss, however, was not statistically significant.   Nature Medicine‘s editors should know better.  So should the New York Times’ editors.  Haspel points out that the New York Times account of the study accepted its conclusion uncritically, headlining it “A Probiotic for Obesity?”  At least the headline included a question mark.  The article did not mention the authors’ patents or conflicts of interest; it should have.

Bottom line: If you want to keep your microbiome healthy, eat a healthy diet.

Jul 31 2019

Junk food encourages overeating: the evidence piles up

I was fascinated to see this article about how offering kids greater amounts and varieties of snack foods encourages them to eat more and, therefore, take in more calories.  Snack variety has a greater effect than just larger package sizes (1).

This article immediately reminded me of the infamous cafeteria diet studies of the late 1980s.  The investigators fed rats all kinds of junk foods and compared the calories they ate to those eaten by control rats allowed only rat chow.  The cafeteria-fed rats ate more (2).

This, of course, is what Kevin Hall and his colleagues found when adults were allowed to eat as much as they wanted of ultraprocessed junk foods (3).

The message is clear: junk food encourages overeating; overeating means taking in more calories; more calories means more weight.  Eating a lot of junk food is a sufficient explanation for obesity.

References

  1.  Kerr JA, et al. Child and adult snack food intake in response to manipulated pre-packaged snack item quantity/variety and snack box size: a population-based randomized trial. International Journal of Obesity (2019).
  2. Prats E, et al.  Energy intake of rats fed a cafeteria diet.  Physiol Behav. 1989 Feb;45(2):263-72.
  3. Hall K, et al.  Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake .  Cell Metabolism 2019; 30:67–77.
Apr 29 2019

A personal memoir of sorts

I was pleased to be invited to contribute to the European Journal of Clinical Nutrition’s “crystal ball” series:

The Crystal Ball Series is a collection of papers from prominent figures in the nutrition field. Through this collection the European Journal of Clinical Nutrition hopes to profile the paths of the eminent individuals [sic] nutrition journey; how they came to it and what have their contributions to nutrition science been. In addition, we ask them to share what they would like to see done now, where they see their area heading, the potential pitfalls, and over all what do they see in their crystal ball for the future of nutrition research.

Here’s my response, titled “A Food lover’s love of nutrition science, policy, and politics.”

Enjoy!