Search results: superfood

Really?  Camel’s milk?  I am indebted to DairyReporter.com for a review of research on the health benefits of camel’s milk.

According to this overview, camel’s milk can

• Prevent colorectal cancer
• Reduce cellular inflammation due to diabetes
• Cures autism
• Enhances immunity
• Cures hepatitis
• Prevents food allergies

A miracle food?

Alas, the article explains, most of these studies were performed in mice or published in journals unlikely to be rigorously peer reviewed.

What can I tell you about the nutritional quality of camel’s milk?

Unfortunately, the USDA’s food composition data base does not have an entry for camel’s milk.  What looks like a reasonable review of the nutritional value of camel’s milk (which you can download from this site) suggests that there are differences in nutrient composition between cow’s and camel’s milks, but the differences are small.  Because the proteins differ, people sensitive or allergic to cow’s milk will have an easier time consuming camel’s milk.

The big issue with camel’s milk in the United States is that it is not pasteurized.  Raw milk carries a greater food safety risk than pasteurized milk.

The FDA also has issued a warning against unproven claims that camel milk prevents autism.

I’m not seeing any particular health benefits from drinking camel milk other than avoiding allergic reactions to cow’s milk.

If you insist on drinking it, make sure it comes from a producer who diligently tests it for pathogens.

Eating Liberally is now interviewing me on a regular basis in a post called “Let’s Ask Marion.” Today’s question is about foods created by technologists to introduce some health benefit–what I like to call “techno-foods.” It is timely because today’s New York Times has a report by Andrew Martin of his visit to the recent convention of the Institute of Food Technology. Are these foods really designed to make you healthy? Or are they about the financial health of their makers?

I’ve posted several studies sponsored by the blueberry industry , most recently on their effects on menopausal symptoms.  Blueberry trade associations, as I discuss in my book Unsavory Truth: How the Food Industry Skews the Science of What We Eat, led the way in promoting research suggesting this fruit is a “superfood.”

If only.

They are still at it, apparently, but sponsorship does not always guarantee the desired outcome.  Here is a rare exception to the rule that industry-sponsored studies almost invariably give results favorable to the sponsor’s marketing interest.  Let’s give credit where it is due.

• The study:  Chronic and postprandial effect of blueberries on cognitive function, alertness, and mood in participants with metabolic syndrome – results from a six-month, double-blind, randomized controlled trial.  The American Journal of Clinical Nutrition.  Available online 6 February 2024, https://doi.org/10.1016/j.ajcnut.2023.12.006
• Methods: “A double-blind, randomized controlled trial was conducted, assessing the primary effect of consuming freeze-dried blueberry powder, compared against an isocaloric placebo, on cardiometabolic health >6 mo and a 24 h postprandial period (at baseline).”
• Results: “Postprandial self-rated calmness significantly improved after 1 cup of blueberries (P = 0.01; q = 0.04; with an 11.6% improvement compared with baseline between 0 and 24 h for the 1 cup group), but all other mood, sleep, and cognitive function parameters were unaffected after postprandial and 6-mo blueberries.”
• Conclusion: “Although self-rated calmness improved postprandially, and significant cognition-metabolite associations were identified, our data did not support strong cognitive, mood, alertness, or sleep quality improvements in MetS participants after blueberry intervention.”
• Conflict of interest: “AC reports financial support provided by the US Highbush Blueberry Council (USHBC) and Biotechnology and Biological Sciences Research Council (BBSRC, UK). AC and EBR both act as advisors and consultants to the United States Highbush Blueberry Council grant committee. All other authors report no conflicts of interest.”
• Funding: “This work was supported by the United States Highbush Blueberry Council with oversight from the USDA and the Biotechnology and Biological Sciences Research Council (United Kingdom). The funders of this research had no involvement in this publication and have placed no restrictions on the publication of these data.”

Comment: In this instance, the last statement could well be correct (it isn’t always, alas).  I like blueberries but they are not a superfood.  There is no such thing as a superfood.  If you want to eat healthfully, by all means eat fruit—and enjoy the ones you like best.

Anne Mendelson.  Spoiled: The Myth of Milk as Superfood.  Columbia University Press, 2023 (396 pages).

I am an admirer of Anne Mendelson’s books and did a blurb for her Chow Chop Suey.  But this one is over the top—original, compelling, brilliantly written.

Driving this book is a question I’ve not heard asked before, at least not so directly: Why and how did the consumption of fresh liquid milk (“drinking-milk”)—as opposed to fermented dairy products—become framed as a nutritional necessity?

Her question derives from some basic facts about cow’s milk and its industrial production:

• Once cow’s milk leaves the udder, it is easily contaminated with pathogenic bacteria.
• Most adults have stopped making the enzyme that digests the sugar lactose in milk and can’t drink it without getting unpleasant digestive systems.
• To produce milk safely requires complicated and expensive industrial processes.
• The cost of milk production exceeds the price people are willing to pay for it; dairy farming is a losing proposition even with taxpayer subsidies.
• Industrial milk production is hard on cows and pollutes the environment.

Why are we even doing this?  For this, she blames 19th and 20th century European and American doctors who thought the ability to digest lactose normal, nutritionists (calcium!), and the USDA (3 servings a day!).

She is not against eating dairy foods when they are fermented.  These, yogurt and the like, are much safer.  Friendly bacteria split the lactose along with producing acid that destroys pathogens.

You don’t have to agree with all her points to appreciate how well they are argued.

To wit:

[The book] argues that influential nutritional theories about fresh and fermented milk took a disastrously wrong turn in the eighteenth century.  The reason is that the founders of modern Western medicine had no way of understanding the genetic fluke that allowed them, unlike most of the world’s peoples, to digest lactose from babyhood to old age.  In other words, today’s mega-industry stemmed from a lack of scientific perspective.  That lack turned the one form of milk that is most fragile, perishable, difficult to produce on a commercial scale, and economically pitfall-strewn into a supposed daily necessity for children and, to a lesser extent, adults.  [pp x, xi].

No other food product is as staggeringly difficult and expensive to get from source (in this case, a cow) to destination (milk glass on table) in something loosely approximating its first condition.  If one existed, it would be treated as an astounding luxury. [p. 1].

Mendelson takes deep dives into the history of dairy use, dietary recommendations, industrial production, and government dairy policy.  In attempting to teach about the Farm Bill, I was defeated by Milk Marketing Orders, the formulas used by the government to set price support levels required to be paid by “handlers” (milk processors) to dairy producers in different areas of the country.  I could not find anything about this in the index, alas, but I loved what she says about them on page 205.

These formulas gradually became as abstruse, and as unintelligible to anyone outside a small charmed circle, as anything in the bad old days before the federal government stepped in.  Far from abolishing the buyer’s market, they trapped farmers selling fluid milk within the marketing order system in endless struggles to wring enough out of handlers to recoup production costs….What I do understand is that as the postwar era advanced, the sheer incomprehensibility of producer-handler milk price schemes again became an endless frustration to dairy farmers, above all those trying to make a living within the marketing order system for drinking-milk.

One final irony:

Nothing is going to dislodge supermarket drinking-milk from its towering economic importance.  It is certain to continue along the track of expansion, consolidation, and increasingly complex technological infrastructure that it has pursued for almost three quarters of a century.  Big Milk is going to become Bigger Milk.  Its absurdities are also sure to become more entrenched.  The greatest of these is the plain fact that Americans are drinking less milk while dairy farms are producing more of it.

A personal comment: The book triggered a memory.  I once visited a school lunch program in Barrow (now Utqiaġvik), Alaska.  Inuit children were served the standard USDA lunch, which requires half-pint cartons of milk.  I did not see any of them drinking it.  The untouched cartons were discarded.  The milk was not only culturally inappropriate, but wasteful.  All food in that part of North Alaska has to be flown in on airplanes.

I learned about this one from NutraIngredients-Europe:

The ‘promising’ role of saffron in stress resilience:  New research conducted in partnership with botanical product manufacturer Pharmactive reveals that its standardized saffron extract Affron was able to normalise HPA [hypothalamic-pituitary-adrenal] axis dysregulation following chronic mild stress stimulation in a rat model…. Read more

I thought this was worth a closer look and went right to the paper.

Effects of Saffron Extract (Affron^®) with 100 mg/kg and 200 mg/kg on Hypothalamic–Pituitary–Adrenal Axis and Stress Resilience in Chronic Mild Stress-Induced Depression in Wistar Rats. Nutrients 2023, 15(23), 4855; https://doi.org/10.3390/nu15234855

Conclusion: These findings elucidate AFN’s [Affron^®] role in stress mitigation, affirm its health benefits, validate its potential as a treatment for stress-related symptoms, confirm its physiological effectiveness, and emphasize its therapeutic promise.

Guess who generated and conducted this study.

Conflict of interest statement: For commercial affiliations, J.K. and S.Y. were employed by the company iCONNECTOME Co., Ltd., which had the roles of curation, formal analysis, and visualization in this study; S.-S.Y. was employed by the company iCONNECTOME Co.,Ltd., which had the roles of conceptualization, funding acquisition, investigation, supervision, review and editing in this study; M.-Y.K. and J.S. were employed by the company Hyundai Bioland Co.,Ltd., which had the roles of methodology and/or writing original draft in this study; M.I.M.-V. was employed by the company Pharmactive Biotech S.L.U., which had the role of investigation in this study. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

In case you wondered, Pharmactive Biotech makes Affron.  The other enterprises do the studies.

Who paid for this?

Funding: This research was funded by Hyundai Bioland Co., Ltd., grant number IC22_02, and Soonchunhyang University Research Fund. Hyundai Bioland Co., Ltd. had the following involvement with the study: participating in the research Investigation, and paid all costs for editing and publishing the Paper. The funder was not involved in the study design, collection, analysis, interpretation of data, the writing of this article or the decision to submit it for publication.

Comment: Huh?  I often suspect that the statement “the funder was not involved….” may not accurately represent the funder’s involvement (to put the matter politely).  In this case,  the role of Hyundai Bioland is self-contradictory.  Its employee-authors say they determined the study’s methods and/or wrote the paper, and the funder says it participated in the research but had no involvement in the study design, etc.  This is confusing, if not contradictory.

I do have to say something about marketing saffron as a superfood.  Saffron consists of the stigmas of crocus flowers, and these are hugely expensive.  Walmart is selling 2 grams for $42.

The Wikipedia entry iexplains why.

The high retail value of saffron is maintained on world markets because of labour-intensive harvesting methods, which require some 440,000 hand-picked saffron stigmas per kilogram…150,000 crocus flowers per kilogram…Forty hours of labour are needed to pick 150,000 flowers…One freshly picked crocus flower yields on average 30 mg of fresh saffron or 7 mg dried; roughly 150 flowers yield 1 g (1⁄32 oz) of dry saffron threads.

Once again, we have here an industry-funded marketing study pretending to be science.  But really, saffron?   OK, an extract that maybe can be synthesized, but still.  There have to be easier and less expensive ways to reduce stress and depression in rats.

Oh.  And in case you were wondering how scientists determine whether rats are depressed?

Our previous animal behavioral assays assessing anxiety and depression, including the elevated plus maze, forced swim, and sucrose preference tests, have revealed that AFN-treated animals (200 mg/kg) exhibit behaviors indicative of anhedonia and depression mitigation [27]. For example, increased consumption of sugar solutions and improved specific escape responses have been observed in forced swim tests.

Ref 27 is: Orio, L.; Alen, F.; Ballesta, A.; Martin, R.; Gomez de Heras, R. Antianhedonic and Antidepressant Effects of Affron^®, a Standardized Saffron (Crocus sativus L.) Extract. Molecules 2020, 25, 3207. [Google Scholar]

I have so many of these waiting to be posted that I might as well do a bunch of them all at once.

Almonds

The study: Prospective Randomized Controlled Trial on the Effects of Almonds on Facial Wrinkles and Pigmentation. Nutrients 2021, 13(3), 785; https://doi.org/10.3390/nu13030785.

Conclusion: “the daily consumption of almonds may contribute to the improvement of facial wrinkles and reduction of skin pigmentation among postmenopausal women with Fitzpatrick skin types I and II.”

Funder: Almond Board of California

Comment: Thanks to Lori Rothman for sending this one.  It’s not the first time I’ve posted an almonds-and-wrinkles study; here’s the other from 2021.   And please note.  It’s not just almonds.  Mangos do this too.  But the Almond Board is working hard on turning almonds into superfoods. Members of the Academy of Nutrition and Dietetics were sent an announcement “Exciting new research investigates the link between almonds and these three key areas: Exercise recovery, prediabetes and skin health. That ad sends you to “Dietitian Tools” on the California Almonds website, where you can find a handy link to the study.

Here’s another one:

The study: Almond intake alters the acute plasma dihydroxy-octadecenoic acid (DiHOME) response to eccentric exercise.Front. Nutr., 09 January 2023  Volume 9 – 2022 | https://doi.org/10.3389/fnut.2022.1042719

Conclusions: “In general, the elevated post-exercise plasma levels of 12,13-DiHOME with almond intake support positive metabolic outcomes for adults engaging in unaccustomed eccentric exercise bouts. Other almond-related benefits for exercisers revealed in this study include reduced feelings of fatigue and tension, better leg-back strength during recovery, and decreased muscle damage during the first day of recovery.”

Funding: This work was supported by Almond Board of California, Modesto, CA. The funder had no role in the study design, data collection, analysis and interpretation, the preparation of the manuscript, or in the decision to submit the article for publication.

Comment: That’s what they all say.

Macadamias

The study: Macadamia nut effects on cardiometabolic risk factors: a randomised trial  J Nutr Sci. 2023.

Conclusion: “Daily consumption of macadamia nuts does not lead [sic]to gains in weight or body fat under free-living conditions in overweight or obese adults; non-significant cholesterol lowering occurred without altering saturated fat intake of similar magnitude to cholesterol lowering seen with other nuts.”

Funding: This study was funded by Hort Innovation, Sydney, Australia (Project code MC17005).  J. J., K. O. and F. M. – None; J. S., S. R. and C. H. have received research funding through their institution from Hort Innovation, Sydney, Australia.  Note: “Hort Innovation is a grower-owned, not-for-profit research and development corporation with the goal of creating value for horticulture growers and those across the horticulture supply chain. It invests more than $120 million in R&D, marketing and trade programs on behalf of industry.”

Peanuts

The study:  Urinary Phenolic Metabolites Associated with Peanut Consumption May Have a Beneficial Impact on Vascular Health Biomarkers. Antioxidants. 2023; 12(3):698. https://doi.org/10.3390/antiox12030698.

Conclusion:  “the present study shows for the first time that regular peanut and peanut butter consumption could have a positive impact on vascular biomarkers in healthy young adults.”

Funding: This research was supported by funding from the Peanut Institute.

Tree Nuts

The study: Tree Nut and Peanut Consumption and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Advances in Nutrition.  May 04, 2023  https://doi.org/10.1016/j.advnut.2023.05.004

Conclusion: “The findings of this review provide evidence of a combined effect of tree nuts and peanuts on a range of biomarkers to create an overall CVD risk reduction.”

Funding: “The findings of this review provide evidence of a combined effect of tree nuts and peanuts on a range of biomarkers to create an overall CVD risk reduction.”

Author disclosures: Two of the authors received previous funding from the International Nut and Dried Fruit Council or the California Walnut Commission.

Comment: If you are interested in doing nut research, trade associations will be happy to fund it.  But maybe only if the results come out the way the funder wants them to?

And another one on tree nuts.

The study: Mixed Tree Nuts, Cognition, and Gut Microbiota: A 4-Week, Placebo-Controlled, Randomized Crossover Trial in Healthy Nonelderly Adults.  J. Nutrition.   VOLUME 152, ISSUE 12, P2778-2788, DECEMBER 2022.  https://doi.org/10.1093/jn/nxac228

Conclusions: “These findings indicate a positive effect of nut on cognition following only 4 wk of consumption in a healthy nonelderly sample, as well as upregulation of a microbial taxa associated with gut health.

Funding: This study was supported by funding from the INC (International Nut and Dried Fruit Council).

Walnuts

The California Walnut Commission and the USDA have put out a request for research proposals on the effects of walnuts on sleep and mental health (I learned about this one from a Tweet (oops, X).  Want to do it?  You can get up to $300,000.

Comment: I guess I don’t have much imagination but I cannot think of a reason why walnuts in particular would have anything to do with sleep or mental health.  But I’ll bet enterprising investigators can figure something out.  Stay tuned on this one.

Overall comment

My point about all of these studies is that you can usually predict who paid for them by their titles and if you know who paid for them, you can pretty well predict what they will find.  Nut trade associations want you to eat more nuts, preferably the kind they represent.  Nuts are just fine for health, but watch the calories.  And do not expect miracles—ever—from eating just one healthy food.

I always appreciate the Headline vs. Study sections of the Obesity and Energetics newsletter that arrives in my email once a week.

This one concerns coffee.  It amuses me that researchers are always trying to prove either that coffee is a superfood or that it is poison.

It’s neither, but never mind.  The research is fun to track.

Headline: Coffee Lowers Risk of Heart Problems and Early Death, Study Says, Especially Ground and Caffeinated.

Researchers found “significant reductions” in the risk for coronary heart disease, congestive heart failure and stroke for all three types of coffee. However, only ground and instant coffee with caffeine reduced the risk for an irregular heartbeat called arrhythmia. Decaffeinated coffee did not lower that risk, according to the study published Wednesday in the European Journal of Preventive Cardiology.

Press-Release: Coffee Drinking Is Associated with Increased Longevity.

Study: Self-Reported Coffee Consumption in the UK Biobank… Again. Causation Not Established.

Drinking two to three cups of coffee a day is linked with a longer lifespan and lower risk of cardiovascular disease compared with avoiding coffee, according to research published today in the European Journal of Preventive Cardiology, a journal of the ESC.¹ The findings applied to ground, instant and decaffeinated varieties.

Headline vs Study Déjà Vu: For More Coffee in the UK Biobank Headlines, See Headline vs Study from July 30, 2021.

• Headline: A Daily Dose of Coffee May Protect You from COVID-19.
• Study: Self-Reported Dietary Behaviors and Incident COVID-19 in the UK Biobank.
• Headline: Too Much Coffee Can Cause Your Brain to Shrink, Raise Risk of Dementia by 53 Percent, Study Finds.
• Study: Associations Among High Coffee Consumption, Brain Volume and Risk of Dementia and Stroke in UK Biobank.
• Headline: Your Morning Cup of Coffee May Lower Your Risk of Liver Disease.
• Study: All Coffee Types are Associated with Lower Risk of Adverse Clinical Outcomes in Chronic Liver Disease: A UK Biobank Study.
• Headline: Coffee Drinking Won’t Harm Your Health, New Study Reveals Caffeine Lowers Arrhythmia Risk.
• Study: Coffee Consumption and Incident Tachyarrhythmias with Mendelian Randomization for Caffeine Metabolism in the UK Biobank.

And just for fun, here’s the Washington Post’s adorable interactive comparison of the relative benefits of coffee vs. tea.

My view?  Drink whichever you like, don’t worry, be happy, enjoy!

***********

For 30% off, go to www.ucpress.edu/9780520384156.  Use code 21W2240 at checkout.

A review article finds it nontoxic.You may recall that on June 17,  Daily Harvest issued a recall of its frozen vegan Crumbles product  after 500 or so adverse event reports, many of  severe liver damage among the 28,000 customers who ordered it.

Here’s what the front of the package looked like.

This product has lots of ingredients:

organic butternut squash, organic hemp seeds, organic cauliflower rice, organic extra virgin olive oil, organic french lentils, organic red lentils, organic tri-colored quinoa, organic cremini mushrooms, organic tara flour, organic leeks, organic parsley, water, organic cassava root flour, organic flax seeds, organic sacha inchi powder, chia seeds, organic porcini powder, himalayan sea salt, organic apple cider vinegar, organic onion powder, nutritional yeast, organic garlic powder, organic tomato powder, organic white pepper, organic coriander seeds, organic mustard powder, organic thyme.

As food safety lawyer Bill Marler predicted, tara flour has been identified as the ingredient at fault.

• Tara is only in Crumbles and Crumbles is the only product that made people sick.
• Tara is also in another company’s product, Revive smoothies, that made people sick.

I had never heard of tara and had to look it up.  Since then, I’ve gotten curious and did some quick research.

Tara is a legume—a bean plant—grown in Peru and other Latin American countries.

Tara is grown for several purposes:

• Pod tannins for industrial leather, keeping ships free of marine animals, and preparing textiles to accept dyes
• Cosmetics (polysaccharides isolated from the seeds)
• Food additives—protein flours and gums (from the endosperm)

The research literature on tara is remarkably extensive (Who knew?).

On the tannins:

• Anything you want to know about tara tannins (from a doctoral dissertation)
• Use of tara tannins to prevent ship fouling

On cosmetics:

• Tara is safe as used in cosmetics.

On tara as a food ingredient:

• An overview from the International Food Additive Council implies that it’s safe
• A major safety evaluation in 1993 says it’s safe.
• It’s not toxic as used in traditional Peruvian medicine
• Another review article finds it nontoxic.
• It is neither mutagenic nor genotoxic
• It may have anti-cancer properties

From everything previously reported about tara over the past 20 years, there is no reason to think it might be unsafe.

So what’s going on?  How to explain “only” hundreds of cases of severe liver injury when 28,000 Crumbles meals were shipped during the time when cases were reported.

Possibilities:

• Some toxic ingredient accidentally or deliberately got into the tara flour (similar to melamine being substituted for wheat gluten in pet food in 2006 and in infant formula in China in 2008).
• Toxic tannins from other parts of the tara plant got into the endosperm flour.
• Some people have unusual sensitivities to tara proteins or digestive products of tara proteins (similar to what happens when people with coeliac disease eat gluten from wheat or other gluten-containing grains)
• Some people have inborn errors of metabolism that cause acute reactions to tara proteins (similar to what happens when people with deficiency of the enzyme glucose-6-phosphate dehydrogenase ingest fava beans)
• Others?  Could be, but I can’t think of any.

To prevent this from happening again, it’s necessary to identify the toxin.  I hope that happens soon.